Uridine-5'-diphosphate disodium salt

Uridine-5'-diphosphate disodium salt Structure
Uridine-5'-diphosphate disodium salt structure
Common Name Uridine-5'-diphosphate disodium salt
CAS Number 27821-45-0 Molecular Weight 628.281
Density N/A Boiling Point N/A
Molecular Formula C15H24N2Na2O18P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 189 , 165-176, (2011)

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits. Recently, facilitated GDP/GTP exchange by non-GPCR GEFs, ...

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

J. Cell Biol. 191 , 367-381, (2010)

A key requirement for Rab function in membrane trafficking is site-specific activation by GDP-GTP exchange factors (GEFs), but the majority of the 63 human Rabs have no known GEF. We have performed a systematic characterization of the 17 human DENN domain pro...

APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.

PLoS ONE 6 , e23676, (2011)

Besides regulation of actin cytoskeleton-dependent functions, Rho GTPase pathways are essential to cell cycle progression and cell division. Rho, Rac and Cdc42 regulate G1 to S phase progression and are involved in cytokinesis. RhoA GDP/GTP cycling is require...

Ubiquitination in Rho signaling.

Curr. Top. Med. Chem 11(23) , 2879-2887, (2011)

The Rho family small GTPases of the Ras superfamily play key roles in regulating diverse signaling pathways that control a myriad of fundamental cellular processes such as cytoskeletal dynamics, cell cycle progression, gene expression, cell polarity, migratio...