Chlorobutanol hemihydrate

Chlorobutanol hemihydrate Structure
Chlorobutanol hemihydrate structure
Common Name Chlorobutanol hemihydrate
CAS Number 6001-64-5 Molecular Weight 372.929
Density N/A Boiling Point 167ºC
Molecular Formula C4H9Cl3O2 Melting Point 75-79ºC
MSDS Chinese USA Flash Point 100ºC
Symbol GHS07
GHS07
Signal Word Warning

An efficient synthesis of a dual PPAR alpha/gamma agonist and the formation of a sterically congested alpha-aryloxyisobutyric acid via a Bargellini reaction.

J. Org. Chem. 70(21) , 8560-3, (2005)

A practical synthesis of benzisoxazole 1 and its conversion to alpha-aryloxyisobutyric acid 2 using 1,1,1-trichloro-2-methyl-2-propanol (chloretone) was developed. Benzisoxazole 1 was formed in high yields by the action of either methanesulfonyl chloride/base...

Application of a capillary electrophoresis method for simultaneous determination of preservatives in pharmaceutical formulations.

J. Sep. Sci. 28(2) , 137-43, (2005)

Preservatives are used to protect pharmaceutical formulations from microbial attack during the period of administration to the patient. Because of their biological activity, preservatives have to be identified and assayed according to the same rules as apply ...

Freeze-drying above room temperature.

J. Pharm. Sci. 88(5) , 501-6, (1999)

This study investigates the use of solid, organic compounds to lyophilize drugs without conventional freeze-drying equipment. The aim of the investigation is to find a pharmaceutically acceptable solvent or solvent combination that is appropriate for freeze-d...