4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one
4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one structure
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Common Name | 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one | ||
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| CAS Number | 1080-12-2 | Molecular Weight | 192.21100 | |
| Density | 1.154g/cm3 | Boiling Point | 348.2ºC at 760 mmHg | |
| Molecular Formula | C11H12O3 | Melting Point | 125-130 °C | |
| MSDS | Chinese USA | Flash Point | 136.9ºC | |
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Alkaloid and sesquiterpenes from the root tuber of Curcuma longa.
Yao Xue Xue Bao 43(7) , 724-7, (2008) One new quinoline alkaloid and seven known bisabolane sesquiterpenes: 2-(2'-methyl-1'-propenyl)-4, 6-dimethyl-7-hydroxyquinoline (1), 2, 5-dihydroxybisabola-3, 10-diene (2), 4, 5-dihydroxybisabola-2,10-diene (3), turmeronol A (4), bisacurone (5), bisacurone A... |
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Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents.
J. Nat. Prod. 69 , 1445-9, (2006) Twenty-eight compounds related to dehydrozingerone (1), isoeugenol (3), and 2-hydroxychalcone (4) were synthesized and evaluated in vitro against human tumor cell replication. Except for isoeugenol analogues 27-35, most compounds exhibited moderate or strong ... |
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Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.
Bioorg. Med. Chem. 15 , 6193-9, (2007) Esterification of glycyrrhetinic acid (GA) with dehydrozingerone (DZ) resulted in a novel cytotoxic GA-DZ conjugate. Based on this exciting finding, we conjugated eleven different DZ analogs with GA or other triterpenoids, including oleanoic acid (OA) or urso... |
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Effects of curcumin and related compounds on processes involving α-hydroxyethyl radicals.
Free Radic. Res. 46(3) , 295-302, (2012) Effects of curcumin and related compounds on product formation in radiolysis of aerated and deaerated ethanol were studied. Ab initio calculations of enthalpy values relating to O-H bond dissociation and H-atom addition to > C = O bonds of the compounds under... |
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Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation.
Cancer Lett. 134(1) , 37-42, (1998) Dehydrozingerone, 4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one, is half an analog of curcumin which is known to have anti-tumor activity. The anti-tumor promoting activity of dehydrozingerone was evaluated by determining the inhibitory effect on Epstein-Barr v... |
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In vitro and in vivo effects of phenolic antioxidants against cisplatin-induced nephrotoxicity.
J. Biochem. 125(2) , 383-90, (1999) We have investigated the effect of phenolic antioxidants on cisplatin-induced cytotoxicity in vero (African Green Monkey Kidney) cells and in rat renal cortical slices in vitro, and on cisplatin-induced nephrotoxicity in rats in vivo. Incubation of cisplatin ... |
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Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function.
J. Cardiovasc. Pharmacol. 52(5) , 422-9, (2008) Growth factor and oxidative stress-mediated migration and proliferation of vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of atherosclerosis. The objective of this study was to assess the ability of dehydrozingerone, a structural ana... |
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Inhibition of albumin denaturation and antiinflammatory activity of dehydrozingerone and its analogs.
Indian J. Exp. Biol. 26(7) , 540-2, (1988)
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In vitro antifungal activity of dehydrozingerone and its fungitoxic properties.
J. Food Sci. 78(1) , M64-9, (2013) The efficacy of Dehydrozingerone (DZ; dehydroderivative of zingerone) as an antifungal agent and its mode of action against food spoilage fungal pathogens was studied and presented. DZ is a constituent of ginger (Zingiber officinale rhizomes) and structural h... |
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Antioxidant properties of dehydrozingerone and curcumin in rat brain homogenates.
Mol. Cell Biochem. 140(1) , 73-9, (1994) The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneous lipid peroxidation. These compounds also inhibi... |