Methyldibromo glutaronitrile
Methyldibromo glutaronitrile structure
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Common Name | Methyldibromo glutaronitrile | ||
|---|---|---|---|---|
| CAS Number | 35691-65-7 | Molecular Weight | 265.933 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 338.6±42.0 °C at 760 mmHg | |
| Molecular Formula | C6H6Br2N2 | Melting Point | 48-50°C | |
| MSDS | Chinese USA | Flash Point | 158.6±27.9 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Allergy to methyldibromoglutaronitrile/phenoxyethanol (Euxyl k 400): regulatory issues, epidemiology, clinical characteristics, and management.
Dermatitis 22(3) , 127-40, (2011) Methyldibromoglutaronitrile/phenoxyethanol (Euxyl K 400) is a preservative found in both personal care products and industrial sources. Although Euxyl K 400 initially appeared to have low sensitizing potential, increased prevalence of contact allergy to Euxyl... |
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Can exposure limitations for well-known contact allergens be simplified? An analysis of dose-response patch test data.
Contact Dermatitis 64(6) , 337-42, (2011) Allergic contact dermatitis is triggered by chemicals in the environment. Primary prevention is aimed at minimizing the risk of induction, whereas secondary and tertiary prevention are aimed at reducing elicitation.To identify the elicitation doses that will ... |
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Hand dermatitis: a focus on allergic contact dermatitis to biocides.
Dermatol. Clin. 27(3) , 251-64, v-vi, (2009) Hand dermatitis is a common disease of the skin resulting in significantly decreased quality of life. Allergic contact dermatitis is a frequent cause of hand dermatitis. Recent studies have revealed that biocides used as preservatives are frequent allergens a... |
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Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008.
Contact Dermatitis 67(5) , 312-4, (2012)
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Temporal trends of preservative allergy in Denmark (1985-2008).
Contact Dermatitis 62(2) , 102-8, (2010) Most cosmetics and industrial products contain preservatives. Preservative allergy is common and, historically, changing contact allergy epidemics caused by preservatives have been observed. In 1997, Alan Dillarstone predicted a stable development of preserva... |
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Patch testing in allergic contact dermatitis: is it useful to perform the cosmetic series in addition to the European standard series?
J. Eur. Acad. Dermatol. Venereol. 24(10) , 1192-6, (2010) Cosmetics are the causative agents in 8-15% of patients suspected of having allergic contact dermatitis. Patch testing with standard series identifies 70-80% of the responsible allergens in all contact dermatitis; however, many important cosmetic-related alle... |
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Determination of bromothalonil residues and degradation in apple and soil by QuEChERS and GC-MS/MS.
Bull. Environ. Contam. Toxicol. 92(4) , 451-4, (2014) The dissipation and residues of bromothalonil in apple and soil under field condition were analyzed by QuEChERS (quick, easy, cheap, effective, rugged and safe) combined with gas chromatography-mass spectrometer method. The recoveries were ranged from 80.8 % ... |
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Proliferative responses in the local lymph node assay associated with concomitant exposure to 1,4-phenylenediamine and methyldibromo glutaronitrile: evidence for synergy?
Contact Dermatitis 59(2) , 90-5, (2008) A key consideration when undertaking risk assessments should be the potential for synergy between contact allergens. Previously, this concept has only been investigated during elicitation in contact allergic individuals.To determine whether there exists evide... |
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Simple and rapid analysis of methyldibromo glutaronitrile in cosmetic products by gas chromatography mass spectrometry.
J. Pharm. Biomed. Anal. 56(5) , 1112-6, (2011) A simple and rapid gas chromatography (GC) method with mass spectrometry (MS) detection has been developed for the determination of methyldibromo glutaronitrile (MDBGN) in cosmetic products. The presence of this preservative in commercial cosmetic samples is ... |
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[Current contact allergens].
Hautarzt 62(10) , 751-6, (2011) Ever-changing exposure to contact allergens, partly due to statutory directives (e.g. nickel, chromate, methyldibromo glutaronitrile) or recommendations from industrial associations (e.g. hydroxyisohexyl 3-cyclohexene carboxaldehyde), requires on-going epidem... |