Benzene-1,4-diammonium chloride

Benzene-1,4-diammonium chloride Structure
Benzene-1,4-diammonium chloride structure
Common Name Benzene-1,4-diammonium chloride
CAS Number 624-18-0 Molecular Weight 181.063
Density 1.15 g/cm3 Boiling Point 267.4ºC at 760 mmHg
Molecular Formula C6H10Cl2N2 Melting Point >200°C
MSDS Chinese USA Flash Point 135.9ºC
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

Interaction of ceruloplasmin with eosinophil peroxidase as compared to its interplay with myeloperoxidase: Reciprocal effect on enzymatic properties.

Free Radic. Res. 49 , 800-11, (2015)

Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are involved in the development of halogenative stress during inflammation. We previously described a complex between MPO and ceruloplasmin (CP). Considering the high structural homology between MPO and EP...

Development and validation of an LC-MS/MS method for determination of p-phenylenediamine and its metabolites in blood samples.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 1-6, (2015)

In some developing countries, p-phenylenediamine (PPD) is used in combination with Henna as hair dye or skin decoration. A sensitive LC-MS/MS method was developed and validated for the simultaneous determination of p-phenylenediamine (PPD) and its metabolites...

Quantitative risk assessment for skin sensitisation: consideration of a simplified approach for hair dye ingredients.

Regul Toxicol Pharmacol 64(3) , 459-65, (2012)

With the availability of the local lymph node assay, and the ability to evaluate effectively the relative skin sensitizing potency of contact allergens, a model for quantitative-risk-assessment (QRA) has been developed. This QRA process comprises: (a) determi...

A 10-year review of p-phenylenediamine allergy and related para-amino compounds at the Ottawa Patch Test Clinic.

Dermatitis 22(6) , 332-4, (2011)

p-Phenylenediamine (PPD) is an important allergen; 5.0% of patients tested positive to PPD when patch-tested, according to the North American Contact Dermatitis Group. Hair dyes are the main source of exposure.To assess the significance of PPD allergy at the ...

N-Acetylation of p-aminobenzoic acid and p-phenylenediamine in primary porcine urinary bladder epithelial cells and in the human urothelial cell line 5637.

J. Toxicol. Environ. Health A 75(19-20) , 1206-15, (2012)

N-Acetyltransferases (NAT) are important enzymes in the metabolism of certain carcinogenic arylamines, as N-acetylation decreases or prevents their bioactivation via N-hydroxylation. To study such processes in the bladder, cell culture models may be used, but...

Prevalence of contact allergy at a dermatology clinic in China from 1990-2009.

Dermatitis 22(6) , 324-31, (2011)

The prevalence of contact allergy varies in different regions and populations.To describe the frequency of sensitization in patients with dermatitis or eczema referred to Peking University First Hospital and analyze the trends in the prevalence of common alle...

Electrochemical characterization of a unique, "neutral" laccase from Flammulina velutipes.

J. Biosci. Bioeng. 115(2) , 159-67, (2013)

The flac1 gene consisted of 1488 bases encodes a novel laccase (Flac1) from Flammulina velutipes. The deduced amino acid sequence of Flac1 with 496 amino acids shows 58-64% homologies with other fungal laccases. The recombinant Flac1 (rFlac1) was heterologous...

Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.

Contact Dermatitis 67(3) , 130-40, (2012)

It is known that, in vitro, human skin bacteria are able to split disperse azo dyes into the corresponding aromatic amines, some of which are sensitizers in the local lymph node assay. We hypothesize that the molecules of disperse dyes migrate onto the skin w...

Unusual localization of allergic contact dermatitis from p-phenylenediamine.

Dermatitis 22(6) , 358, (2011)

Contact dermatitis to hair dye: an update.

Indian J. Dermatol. Venereol. Leprol. 78(5) , 583-90, (2012)

Exposure to hair dyes has long been known as a significant risk factor for development of allergic contact dermatitis among the exposed population as these lead to severe eczema of face and upper trunk in the consumer and hand eczema in hair-dressers. Current...