toltrazuril

toltrazuril Structure
toltrazuril structure
Common Name toltrazuril
CAS Number 69004-03-1 Molecular Weight 425.382
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H14F3N3O4S Melting Point 194-196°C
MSDS Chinese USA Flash Point N/A
Symbol GHS09
GHS09
Signal Word Warning

Pharmacokinetics and improved bioavailability of toltrazuril after oral administration to rabbits.

J. Vet. Pharmacol. Ther. 33(5) , 503-6, (2010)

Necrotic enteritis due to simultaneous infection with Isospora suis and clostridia in newborn piglets and its prevention by early treatment with toltrazuril.

Parasitol. Res. 110(4) , 1347-55, (2012)

In this study, 51 piglets originating from five different sows were included in the investigations. The animal source of all sows had a history of Clostridium perfringens type A (β2) infection. The piglets of three sows (n = 31) were experimentally infected w...

Determination of diclazuril, toltrazuril and its two metabolites in poultry tissues and eggs by gel permeation chromatography-liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(20) , 1757-63, (2011)

A new procedure has been described for the extraction of diclazuril (DIZ), toltrazuril (TOZ) and its two main metabolites toltrazuril sulphoxide (TZSO) and toltrazuril sulphone (TZS) from poultry tissues and eggs, using gel permeation chromatography (GPC). Th...

Comparison of toltrazuril and sulphadimethoxine in the treatment of intestinal coccidiosis in pet rabbits.

Vet. Rec. 167(8) , 287-90, (2010)

Treatment of intestinal coccidiosis was studied in domestic pet rabbits. In 45 rabbits aged four months or more, coccidial oocysts were observed in the faeces of 35 rabbits at a mean density of 806 opg (range 50 to 6800 opg). Eimeria magna was the dominant sp...

Efficacy of sulfonamides and Baycox(®) against Isospora suis in experimental infections of suckling piglets.

Parasitol. Res. 109(6) , 1653-9, (2011)

Sulfonamide treatment of piglets against neonatal coccidiosis has frequently been suggested in the literature. In order to evaluate the efficacy of sulfonamides against experimental Isospora suis infections in suckling piglets (oral infection with 1,500 sporu...

Failure of combination therapy with imidocarb dipropionate and toltrazuril to clear Hepatozoon canis infection in dogs.

Parasitol. Res. 109(3) , 919-26, (2011)

Current treatments with imidocarb dipropionate for infected dogs with Hepatozoon canis do not always provide parasitological cure. The objective of this study is to determine whether concomitant use of toltrazuril may potentiate the effect of imidocarb diprop...

Factors associated with the occurrence and level of Isospora suis oocyst excretion in nursing piglets of Greek farrow-to-finish herds.

BMC Vet. Res. 8 , 228, (2012)

Piglet isosporosis is one of the most common parasitic diseases in modern pig production. To prevent clinical disease, prophylactic treatment of piglets with toltrazuril (BAYCOX® 5%, Bayer HealthCare, Animal Health, Monheim, Germany) is widely practiced in th...

In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: a novel strategy for prevention of human exposure to meat-borne toxoplasmosis.

Res. Vet. Sci. 94(2) , 269-76, (2013)

The aim of the present study was to investigate in vivo efficacy of toltrazuril on Toxoplasma gondii tissue cysts following induction of chronic toxoplasmosis in 4-week-old lambs (n=27) by inoculation of 1×10(5) T. gondii ME 49 strain oocysts (day 0). Beginni...

Modulation of specific biochemical blood parameters by helminth infection in laboratory Beagle dogs.

Pol. J. Vet. Sci. 15(2) , 387-9, (2012)

The objective of this study was to examine the independent effect of helminths infection on biochemical blood parameters in Beagles intended for laboratory use which may contribute to a change of experimental results. As a result of research, the authors conf...

Relevance and treatment of coccidiosis in domestic pigeons (Columba livia forma domestica) with particular emphasis on toltrazuril.

J. Avian Med. Surg. 23(1) , 1-5, (2009)

Coccidia are common pathogenic parasites in pigeons (Columba livia). Coccidiosis is most commonly seen in young pigeons and only rarely in adult birds. Infections in domestic pigeons are typically mixed and commonly include Eimeria columbarum and Eimeria labb...