p-Toluenesulfonyl isocyanate

p-Toluenesulfonyl isocyanate Structure
p-Toluenesulfonyl isocyanate structure
Common Name p-Toluenesulfonyl isocyanate
CAS Number 4083-64-1 Molecular Weight 197.211
Density 1.3±0.1 g/cm3 Boiling Point 288.8±9.0 °C at 760 mmHg
Molecular Formula C8H7NO3S Melting Point 5°C
MSDS Chinese USA Flash Point 128.5±18.7 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Palladium-catalyzed tandem bis-allylation of isocyanates.

Org. Lett. 3(6) , 909-12, (2001)

A tandem bis-allylation of p-toluenesulfonyl isocyanate can be achieved by palladium-catalyzed three-component coupling reaction with allylstannanes and allyl chlorides. A high level of regioselectivity can be obtained by the appropriate choice of the allylic...

Determination of 3-α-hydroxytibolone in human plasma by LC-MS/MS: application for a pharmacokinetic study after administration of a tibolone formulation.

Biomed. Chromatogr. 27(11) , 1457-62, (2013)

A new method was developed for the quantitation of 3-α-hydroxy tibolone, in human plasma, after oral administration of a tablet formulation containing tibolone (2.5 mg). 3-α-Hydroxy tibolone was extracted by a liquid-liquid procedure, using cyproterone acetat...

Simultaneous determination of diethylene glycol and propylene glycol in pharmaceutical products by HPLC after precolumn derivatization with p-toluenesulfonyl isocyanate.

J. Sep. Sci. 30(16) , 2620-7, (2007)

A simple and reliable HPLC method was developed for the simultaneous quantitative analysis of diethylene glycol (DEG) and propylene glycol (PG) in pharmaceutical products by precolumn derivatization. The derivatization reagent p-toluenesulfonyl isocyanate (TS...

Pyrrolizidine alkaloids in herbal teas for infants, pregnant or lactating women.

Food Chem. 187 , 491-8, (2015)

A general contamination of tea with pyrrolizidine alkaloids (PA) has just become known. Here, we report the application and modification of a new HPLC-ESI-MS/MS sum parameter method to quantitate PA content of herbal teas intended for infants, pregnant and la...

J. Org. Chem. 58 , 7022, (1993)

Tetrahedron Lett. 34 , 1867, (1993)

Tetrahedron Lett. 34 , 951, (1993)

Tetrahedron 47 , 2263, (1991)