Lincomycin Hydrochloride Monohydrate

Lincomycin Hydrochloride Monohydrate Structure
Lincomycin Hydrochloride Monohydrate structure
Common Name Lincomycin Hydrochloride Monohydrate
CAS Number 7179-49-9 Molecular Weight 461.014
Density N/A Boiling Point 646.8ºC at 760 mmHg
Molecular Formula C18H37ClN2O7S Melting Point 154 °C
MSDS USA Flash Point 345ºC

Performance characterization of a quantitative liquid chromatography-tandem mass spectrometric method for 12 macrolide and lincosamide antibiotics in salmon, shrimp and tilapia.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 203-10, (2014)

This paper describes an extension and performance characterization of a quantitative confirmatory multi-residue liquid chromatography-tandem mass spectrometric method for residues of macrolide and lincosamide antibiotics, originally validated for application ...

Gene expression of ribosomal protein mRNA inChironomus riparius: Effects of endocrine disruptor chemicals and antibiotics

Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 156(2) , 113-20, (2012)

Ribosomal protein genes are essential for cellular development. To examine the effects of ribosomal protein genes under various cellular stress conditions in chironomids, ribosomal protein S3 (RpS3) and S6 (RpS6) cDNA from Chironomus riparius were characteriz...

Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants.

Ecotoxicol. Environ. Saf. 108 , 52-7, (2014)

Pharmaceutically active compounds (PACs) are continuously dispersed into the environment due to human and veterinary use, giving rise to their potential accumulation in edible plants. In this study, Eruca sativa L. and Zea mays L. were selected to determine t...

Iron is involved in the maintenance of circadian period length in Arabidopsis.

Plant Physiol. 161(3) , 1409-20, (2013)

The homeostasis of iron (Fe) in plants is strictly regulated to maintain an optimal level for plant growth and development but not cause oxidative stress. About 30% of arable land is considered Fe deficient because of calcareous soil that renders Fe unavailab...

[Functional state of the ileum, cationic peptids and zinc content in the Paneth cells of the rats following lincomycin, indomethacin and methotrexate andministration].

Fiziol. Zh. 59(3) , 78-88, (2013)

In the paper the relation between the changes of a functional condition of ileum, composition of its microflora and secretory activity of Paneth cells has been investigated. Administration of lincomycin led to a reduction of total of symbiotic bacteria and ap...

Biochemistry: Elusive source of sulfur unravelled.

Nature 518(7537) , 45-6, (2015)

Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.

Nature 518(7537) , 115-9, (2015)

Low-molecular-mass thiols in organisms are well known for their redox-relevant role in protection against various endogenous and exogenous stresses. In eukaryotes and Gram-negative bacteria, the primary thiol is glutathione (GSH), a cysteinyl-containing tripe...

Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation.

RNA 19(2) , 158-66, (2013)

In the absence of elongation factor EF-G, ribosomes undergo spontaneous, thermally driven fluctuation between the pre-translocation (classical) and intermediate (hybrid) states of translocation. These fluctuations do not result in productive mRNA translocatio...

Optimisation and validation of a quantitative and confirmatory method for residues of macrolide antibiotics and lincomycin in kidney by liquid chromatography coupled to mass spectrometry.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(4) , 587-95, (2012)

A solid phase extraction followed by a liquid chromatography (LC)-tandem mass spectrometry (MS/MS) detection method for the confirmatory analysis of lincomycin (LIN), clindamycin (CLI), tilmicosin (TIM), erythromycin (ERI) and tylosin (TYL) residues in kidney...

Wavelength-dependent photodamage to Chlorella investigated with a new type of multi-color PAM chlorophyll fluorometer.

Photosynth. Res. 114(3) , 165-77, (2013)

A new type of multi-color PAM chlorophyll fluorometer (Schreiber et al. 2012) was applied for measurements of photodamage to photosystem II (PS II) in optically thin suspensions of Chlorella (200 μg Chl l(-1)) in the presence of 1 mM lincomycin. An action spe...