Isopentenyl phosphate dilithium salt

Isopentenyl phosphate dilithium salt Structure
Isopentenyl phosphate dilithium salt structure
Common Name Isopentenyl phosphate dilithium salt
CAS Number 18687-42-8 Molecular Weight 177.97800
Density N/A Boiling Point N/A
Molecular Formula C5H9Li2O4P Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates.

ACS Chem. Biol. 5 , 589-601, (2010)

The biosynthesis of isopentenyl diphosphate (IPP) from either the mevalonate (MVA) or the 1-deoxy-d-xylulose 5-phosphate (DXP) pathway provides the key metabolite for primary and secondary isoprenoid biosynthesis. Isoprenoid metabolism plays crucial roles in ...

Characterization of thermophilic archaeal isopentenyl phosphate kinases.

Biochemistry 49 , 207-217, (2010)

Archaea synthesize isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), the essential building blocks of isoprenoid compounds, from mevalonate (MVA). However, an analysis of the genomes of several members of the Archaea failed to identify gene...

Mutagenesis of isopentenyl phosphate kinase to enhance geranyl phosphate kinase activity.

ACS Chem. Biol. 7 , 1241-1246, (2012)

Isopentenyl phosphate kinase (IPK) catalyzes the ATP-dependent phosphorylation of isopentenyl phosphate (IP) to form isopentenyl diphosphate (IPP) during biosynthesis of isoprenoid metabolites in Archaea. The structure of IPK from the archeaon Thermoplasma ac...

An improved synthesis of isopentenyl pyrophosphate.

Biochem. J. 105 , 545-547, (1967)

1. Isopentenol was converted into isopentenyl phosphate with phosphoryl chloride in ether containing pyridine. 2. The isopentenyl phosphate reacted in 2-methylpropan-2-ol-water with morpholine and dicyclohexylcarbodi-imide to give isopentenyl phosphoromorphol...

The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.

Biochemistry 51 , 917-925, (2012)

Isopentenyl phosphate kinase (IPK) catalyzes the phosphorylation of isopentenyl phosphate to form the isoprenoid precursor isopentenyl diphosphate in the archaeal mevalonate pathway. This enzyme is highly homologous to fosfomycin kinase (FomA), an antibiotic ...