CCT007093

CCT007093 Structure
CCT007093 structure
Common Name CCT007093
CAS Number 176957-55-4 Molecular Weight 272.385
Density 1.4±0.1 g/cm3 Boiling Point 484.7±45.0 °C at 760 mmHg
Molecular Formula C15H12OS2 Melting Point 222-223℃
MSDS Chinese USA Flash Point 246.9±28.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Wip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to γ-radiation.

Cell Death Dis. 4 , e744, (2013)

Wild-type p53-induced phosphatase 1 (Wip1) is a p53-inducible serine/threonine phosphatase that switches off DNA damage checkpoint responses by the dephosphorylation of certain proteins (i.e. p38 mitogen-activated protein kinase, p53, checkpoint kinase 1, che...

RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.

Breast Cancer Res. 12 , R41, (2010)

Paclitaxel is a widely used drug in the treatment of patients with locally advanced and metastatic breast cancer. However, only a small portion of patients have a complete response to paclitaxel-based chemotherapy, and many patients are resistant. Strategies ...