TNPAL-Sphingomyelin
TNPAL-Sphingomyelin structure
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Common Name | TNPAL-Sphingomyelin | ||
|---|---|---|---|---|
| CAS Number | 117985-56-5 | Molecular Weight | 873.02500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C41H73N6O12P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 11ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Rapid phase change of lipid microdomains in giant vesicles induced by conversion of sphingomyelin to ceramide.
Biochim. Biophys. Acta 1758(2) , 145-53, (2006) To understand the role of sphingomyelinase (SMase) in the function of biological membranes, we have investigated the effect of conversion of sphingomyelin (SM) to ceramide (Cer) on the assembly of domains in giant unilamellar vesicles (GUVs). The GUVs were pr... |
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Interaction between sphingomyelin and oxysterols contributes to atherosclerosis and sudden death.
Am. J. Cardiovasc. Dis. 3(1) , 17-26, (2013) Despite major public health efforts, coronary heart disease continues to be the leading cause of death in the United States. Oxidized lipids contribute to heart disease both by increasing deposition of calcium on the arterial wall, a major hallmark of atheros... |
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Sphingomyelin metabolism at the plasma membrane: Implications for bioactive sphingolipids
FEBS Lett. 584(9) , 1887-94, (2010) The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and SM ... |
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Identification of the teichoic acid phosphorylcholine esterase in Streptococcus pneumoniae.
Mol. Microbiol. 39(6) , 1610-22, (2001) Streptococcus pneumoniae is a major human pathogen and many interactions of this bacterium with its host appear to be mediated, directly or indirectly, by components of the bacterial cell wall, specifically by the phosphorylcholine residues which serve as anc... |
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Effect of endurance training on the sphingomyelin-signalling pathway activity in the skeletal muscles of the rat.
J. Physiol. Pharmacol. 55(2) , 305-13, (2004) The sphingomyelin signalling pathway has been shown to function in different skeletal muscle types. The aim of the present study was to examine the effect of endurance training on the functioning of the pathway in the muscles. The experiments were carried out... |
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A spectrophotometric method for determination of sphingomyelinase.
Biochim. Biophys. Acta 530 , 503, (1978) A colored derivative of sphingomyelin was synthesized and used as substrate for several sphingomyelinases. The compound is N-omega-trinitrophenyl-aminolaurylsphingosylphosphorylcholine. The rate of hydrolysis of this substrate was compared to that of bovine b... |