L-Methionine-13C,d3

L-Methionine-13C,d3 Structure
L-Methionine-13C,d3 structure
Common Name L-Methionine-13C,d3
CAS Number 73488-65-0 Molecular Weight 153.22200
Density N/A Boiling Point N/A
Molecular Formula C413CH8D3NO2S Melting Point 273ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

5-Hydroxymethylcytosine is a predominantly stable DNA modification.

Nature Chemistry 6(12) , 1049-55, (2014)

5-Hydroxymethylcytosine (hmC) is an oxidation product of 5-methylcytosine which is present in the deoxyribonucleic acid (DNA) of most mammalian cells. Reduction of hmC levels in DNA is a hallmark of cancers. Elucidating the dynamics of this oxidation reaction...

5-Formylcytosine can be a stable DNA modification in mammals.

Nat. Chem. Biol. 11(8) , 555-7, (2015)

5-Formylcytosine (5fC) is a rare base found in mammalian DNA and thought to be involved in active DNA demethylation. Here, we show that developmental dynamics of 5fC levels in mouse DNA differ from those of 5-hydroxymethylcytosine (5hmC), and using stable iso...