NSC697923

NSC697923 Structure
NSC697923 structure
Common Name NSC697923
CAS Number 343351-67-7 Molecular Weight 267.25800
Density N/A Boiling Point N/A
Molecular Formula C11H9NO5S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.

ACS Chem. Biol. 10(7) , 1718-28, (2015)

Ubc13 is an E2 ubiquitin conjugating enzyme that functions in nuclear DNA damage signaling and cytoplasmic NF-κB signaling. Here, we present the structures of complexes of Ubc13 with two inhibitors, NSC697923 and BAY 11-7082, which inhibit DNA damage and NF-κ...