7-aminonitrazepam
7-aminonitrazepam structure
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Common Name | 7-aminonitrazepam | ||
|---|---|---|---|---|
| CAS Number | 4928-02-3 | Molecular Weight | 251.28300 | |
| Density | 1.3g/cm3 | Boiling Point | 495.8ºC at 760 mmHg | |
| Molecular Formula | C15H13N3O | Melting Point | 242-244ºC | |
| MSDS | N/A | Flash Point | 253.6ºC | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Measurement of benzodiazepines in urine by liquid chromatography-tandem mass spectrometry: confirmation of samples screened by immunoassay.
Ann. Clin. Biochem. 47(Pt 2) , 111-7, (2010) Liquid chromatography linked to tandem mass spectrometry (LC/MS/MS) provides the ability to identify a range of benzodiazepines in accordance with European Union criteria and is an attractive method for the confirmation of benzodiazepines following immunoassa... |
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A highly sensitive method for the determination of 7-aminonitrazepam, a metabolite of nitrazepam, in human urine using high-performance electrospray liquid chromatography tandem mass spectrometry.
Biomed. Chromatogr. 23(7) , 740-4, (2009) A highly sensitive method has been developed for the determination of urinary 7-aminonitrazepam (7-ANZP), the major metabolite of nitrazepam, using high-performance electrospray liquid chromatography tandem mass spectrometry. The samples were prepared for ana... |
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Determination of nitrazepam and its main metabolites in urine by thin-layer chromatography and direct densitometry.
J. Chromatogr. A. 339(1) , 163-9, (1985) A method for the direct quantitative densitometry of nitrazepam and its main metabolites (7-aminonitrazepam, 7-acetamidonitrazepam and 2-amino-5-nitrobenzophenone) in urine was developed. The unchanged drug and its metabolites were extracted with benzene-dich... |
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[Analysis of 7-aminonitrazepam in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry].
Se Pu 20(5) , 394-7, (2002) A highly sensitive method has been developed for the analysis of 7-aminonitrazepam (7-ANIZ), the major metabolite of nitrazepam, in urine by trimethylsilyl derivatization-gas chromatography/mass spectrometry. Urine samples were extracted with ethyl ether-ethy... |
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Simultaneous determination of nitrazepam and its metabolites in urine by micellar electrokinetic capillary chromatography.
J. Chromatogr. A. 621(2) , 249-55, (1993) We applied micellar electrokinetic capillary chromatography to simultaneous separation and determination of nitrazepam and its major metabolites, 7-aminonitrazepam and 7-acetamidonitrazepam, in spiked urine. Prior to electrophoresis, the three compounds were ... |
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High-performance liquid chromatographic determination of nitrazepam and its metabolites in human urine.
J. Chromatogr. A. 310(1) , 213-8, (1984)
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Comparative developmental toxicity and metabolism of nitrazepam in rats and mice.
Toxicol. Appl. Pharmacol. 121(2) , 233-8, (1993) This study was designed to evaluate the developmental toxicity of nitrazepam (NZ) in Sprague-Dawley rats and ICR mice and to determine the metabolic factors which modulate susceptibility to the developmental effects of NZ. Rats were treated orally with a sing... |
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Simple preparation of the major urinary metabolites of flunitrazepam and nitrazepam.
Ir. J. Med. Sci. 168(1) , 8-9, (1999) An alarming increase in the misuse/abuse of nitrobenzodiazepine derivatives, especially flunitrazepam, prompted us to establish reliable analytical protocols for their routine detection. Whilst the parent drugs are readily available from a number of commercia... |
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Tissue distribution of nitrazepam and 7-aminonitrazepam in a case of nitrazepam intoxication.
Forensic Sci. Int. 131(2-3) , 108-12, (2003) We report a case of nitrazepam poisoning in which the distribution of nitrazepam and 7-aminonitrazepam was determined in body fluids and tissues. A 52-year-old woman was found dead in a shallow ditch (approximately 5 cm in depth), in the winter. Ambient tempe... |
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The stability of benzodiazepines in saliva.
Methods Find. Exp. Clin. Pharmacol. 10(1) , 21-6, (1988) The stability of some selected benzodiazepines in saliva has been studied. The benzodiazepines nitrazepam and clonazepam were found to be unstable in saliva at room temperature and nitrazepam was converted into 7-aminonitrazepam. The conversion rate of nitraz... |