Docosahexaenoic Acid
Docosahexaenoic Acid structure
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Common Name | Docosahexaenoic Acid | ||
|---|---|---|---|---|
| CAS Number | 6217-54-5 | Molecular Weight | 328.488 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 446.7±24.0 °C at 760 mmHg | |
| Molecular Formula | C22H32O2 | Melting Point | -44ºC | |
| MSDS | Chinese USA | Flash Point | 343.4±18.0 °C | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, nutritionists and members of the metabolomics community. Si... |
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The human serum metabolome.
PLoS ONE 6(2) , e16957, (2011) Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite ref... |
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Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes.
Biochim. Biophys. Acta 1837(6) , 783-91, (2014) Skeletal muscle is a key organ of mammalian energy metabolism, and its mitochondria are multifunction organelles that are targets of dietary bioactive compounds. The goal of this work was to examine the regulation of mitochondrial dynamics, functionality and ... |
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Resolvin D2 supports MCF-7 cell proliferation via activation of estrogen receptor.
J. Pharmacol. Exp. Ther. 351(1) , 172-80, (2014) Inflammation has been implicated in tumor initiation, angiogenesis, and metastasis, and linked to the development of more aggressive, therapy-resistant estrogen receptor (ER)-positive breast cancer. Resolvin D2 (RvD2) is a potent anti-inflammatory lipid media... |
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Folate and methylation status in relation to phosphorylated tau protein(181P) and beta-amyloid(1-42) in cerebrospinal fluid.
Clin. Chem. 53(6) , 1129-36, (2007) Increased plasma total homocysteine (tHcy) is a risk factor for neurological diseases, but the underlying pathophysiology has not been adequately explained.We evaluated concentrations of tHcy, S-adenosyl homocysteine (SAH), S-adenosyl methionine (SAM), folate... |
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Docosahexaenoic acid counteracts attenuation of CD95-induced cell death by inorganic mercury.
Toxicol. Appl. Pharmacol. 282(1) , 61-7, (2015) In the United States the principal environmental exposure to mercury is through dietary consumption of sea food. Although the mechanism by which low levels of mercury affect the nervous system is not well established, epidemiological studies suggest that low ... |
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Functional characterization of the duck and turkey fatty acyl elongase enzymes ELOVL5 and ELOVL2.
J. Nutr. 144(8) , 1234-9, (2014) In most Western countries, the consumption of fish is low and insufficient to provide the recommended daily intake of the n-3 (ω-3) long-chain polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3). Po... |
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The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant?
J. Immunol. 193(12) , 6031-40, (2014) Influenza viruses remain a critical global health concern. More efficacious vaccines are needed to protect against influenza virus, yet few adjuvants are approved for routine use. Specialized proresolving mediators (SPMs) are powerful endogenous bioactive reg... |
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Lipidomics reveals a remarkable diversity of lipids in human plasma.
J. Lipid Res. 51(11) , 3299-305, (2010) The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a regular part of every patient's blood test and physicians r... |