Mirin
Mirin structure
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Common Name | Mirin | ||
|---|---|---|---|---|
| CAS Number | 299953-00-7 | Molecular Weight | 220.248 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 441.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C10H8N2O2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 220.8±31.5 °C | |
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Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.
J. Virol. 88(15) , 8528-44, (2014) Activation of the ATM (ataxia telangiectasia-mutated kinase)-dependent DNA damage response (DDR) is necessary for productive replication of human papillomavirus 31 (HPV31). We previously found that DNA repair and homologous recombination (HR) factors localize... |
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DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.
Mol. Cell. 53(1) , 7-18, (2014) MRE11 within the MRE11-RAD50-NBS1 (MRN) complex acts in DNA double-strand break repair (DSBR), detection, and signaling; yet, how its endo- and exonuclease activities regulate DSBR by nonhomologous end-joining (NHEJ) versus homologous recombination (HR) remai... |
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A central role of TRAX in the ATM-mediated DNA repair.
Oncogene 35 , 1657-70, (2016) DNA repair is critical for the maintenance of genome stability. Upon genotoxic stress, dysregulated DNA repair may induce apoptosis. Translin-associated factor X (TRAX), which was initially identified as a binding partner of Translin, has been implicated in g... |
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The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.
Cell Death Differ. 23 , 197-206, (2016) The MRE11/RAD50/NBS1 (MRN) complex is a major sensor of DNA double strand breaks, whose role in controlling faithful DNA replication and preventing replication stress is also emerging. Inactivation of the MRN complex invariably leads to developmental and/or d... |