Fmoc-Val-OH
Fmoc-Val-OH structure
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Common Name | Fmoc-Val-OH | ||
|---|---|---|---|---|
| CAS Number | 68858-20-8 | Molecular Weight | 339.385 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 551.8±33.0 °C at 760 mmHg | |
| Molecular Formula | C20H21NO4 | Melting Point | 143-147ºC | |
| MSDS | USA | Flash Point | 287.5±25.4 °C | |
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Aspartate-modified doxorubicin on its N-terminal increases drug accumulation in LAT1-overexpressing tumors.
Cancer Sci. 106 , 747-56, (2015) L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherapeutic agent. We screened doxorubicin modified by seven diff... |
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Cell-penetrating apoptotic peptide/p53 DNA nanocomplex as adjuvant therapy for drug-resistant breast cancer.
Mol. Pharm. 11(10) , 3352-60, (2014) Drug resistance becomes a formidable challenge against effective cancer therapy. Defective apoptosis in cancer cells is a key factor responsible for chemoresistance or radioresistance. Promoting apoptosis is an important method to sensitize the resistant cell... |
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Design and synthesis of newN-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents
Eur. J. Med. Chem. 44 , 1933-40, (2009) Twenty-four new dipeptide analogs ( 1– 24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycar... |
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Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.
PLoS ONE 4 , e7191, (2009) Temporins are antimicrobial peptides secreted by the granular glands of the European red frog (Rana temporaria). They are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. This study shows that a synthetic temporin B analog... |