5-hydroxy-N-methyl Tryptamine (oxalate)

5-hydroxy-N-methyl Tryptamine (oxalate) Structure
5-hydroxy-N-methyl Tryptamine (oxalate) structure
Common Name 5-hydroxy-N-methyl Tryptamine (oxalate)
CAS Number 1975-81-1 Molecular Weight 280.27700
Density N/A Boiling Point 402.6ºC at 760mmHg
Molecular Formula C13H16N2O5 Melting Point 161-162ºC
MSDS Chinese USA Flash Point 197.3ºC
Symbol GHS07
GHS07
Signal Word Warning

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-N omega-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection.

J. Chromatogr. A. 430(2) , 381-7, (1988)

In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.

J. Agric. Food Chem. 56(24) , 11718-26, (2008)

Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the active constituent(s) and mechanism(s) of action remain unknown. Because seroto...

No evidence for a physiological role of 5-hydroxykynuramine in chicken hemostasis.

Agents Actions 16(5) , 443-5, (1985)

Pharmacological effects of 5-hydroxykynuramine (5-HK) were investigated in chicken whole blood. It was shown that 5-HK had a time-depending inhibiting activity on platelet aggregation induced by 5-hydroxytryptamine (5-HT). Experiments were carried out in orde...

5-HT2 receptor-controlled modulation of medullary respiratory neurones in the cat.

J. Physiol. 487 ( Pt 3) , 653-61, (1995)

1. The effects of the 5-HT2 receptor agonist alpha-methyl-5-HT were studied on the membrane of expiratory (E2) and post-inspiratory (PI) neurones, by intracellular recordings in the caudal medulla of anaesthetized cats. 2. Ionophoresis of alpha-Me-5-HT depola...

Electrophysiological evidence for a functional interaction between 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex: an iontophoretic study.

Synapse 17(3) , 173-81, (1994)

In this study, we examined the interaction of 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5-HT1A receptor agonist...

Modulation of peripheral markers of the serotoninergic system in healthy horses

Res. Vet. Sci. 90(3) , 392-5, (2011)

To evaluate the changes in plasma and platelet serotonin (5-HT) as markers of the serotoninergic system in equines, 5-HT content was measured by high performance liquid chromatography (HPLC) in deproteinized plasma obtained from peripheral blood samples of 12...

Excitation and inhibition of rat medial vestibular nucleus neurones by 5-hydroxytryptamine.

Exp. Brain Res. 93(2) , 293-8, (1993)

The effects of 5-hydroxytryptamine (5-HT) and related compounds on the discharge rate of tonically active medial vestibular nucleus (MVN) neurones were studied in an in vitro slice preparation of the dorsal brainstem of the rat. The majority (87 of 107, 82%) ...

Interference of paracetamol (acetaminophen) with a commercially available high-performance liquid chromatography analysis of serotonin leading to falsely low serotonin levels.

Ann. Clin. Biochem. 46(Pt 2) , 146-8, (2009)

Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of parac...

Isolation of N,N-dimethyl and N-methylserotonin 5-O-β-glucosides from immature Zanthoxylum piperitum seeds.

Biosci. Biotechnol. Biochem. 74(9) , 1951-2, (2010)

Two serotonin derivatives, N,N-dimethylserotonin 5-O-β-glucoside (1a) and N-methylserotonin 5-O-β-glucoside (1b) were isolated from immature seeds of Zanthoxylum piperitum. Their structures were determined by multi-step conversion reactions and spectroscopic ...