2-Chloromandelic acid
2-Chloromandelic acid structure
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Common Name | 2-Chloromandelic acid | ||
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| CAS Number | 10421-85-9 | Molecular Weight | 186.592 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 350.3±27.0 °C at 760 mmHg | |
| Molecular Formula | C8H7ClO3 | Melting Point | 80-85ºC | |
| MSDS | Chinese USA | Flash Point | 165.7±23.7 °C | |
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QSAR-based solubility model for drug-like compounds.
Bioorg. Med. Chem. 18 , 7078-84, (2010) Solubility plays a very important role in the selection of compounds for drug screening. In this context, a QSAR model was developed for predicting water solubility of drug-like compounds. First, a set of relevant parameters for establishing a drug-like chemi... |
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Modeling the retention mechanism for high-performance liquid chromatography with a chiral ligand mobile phase and enantioseparation of mandelic acid derivatives.
J. Sep. Sci. 38 , 2085-92, (2015) The chromatographic retention mechanism describing relationship between retention factor and concentration of Cu(2+) (l-phenylalanine)2 using chiral ligand mobile phase was investigated and eight mandelic acid derivatives were enantioseparated by chiral ligan... |
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Resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine: chiral discrimination mechanism.
Chirality 24(5) , 349-55, (2012) During the resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine, the crystals of the less soluble salt were grown, and their structure were determined and presented. The chiral discrimination mechanism was investigated by examining the... |
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Identification and characterization of solid-state nature of 2-chloromandelic acid.
J. Pharm. Sci. 98(5) , 1835-44, (2009) The racemate and enantiomers of 2-chloromandelic acid were characterized by SS-NMR, XRPD, and FTIR. The binary melting point phase diagram was constructed by DSC (differential scanning calorimetry). The solid-state nature of 2-chloromandelic acid was identifi... |