tert-Butyl 4-aminobenzoate

tert-Butyl 4-aminobenzoate Structure
tert-Butyl 4-aminobenzoate structure
Common Name tert-Butyl 4-aminobenzoate
CAS Number 18144-47-3 Molecular Weight 193.242
Density 1.1±0.1 g/cm3 Boiling Point 322.4±15.0 °C at 760 mmHg
Molecular Formula C11H15NO2 Melting Point 108-110 °C
MSDS Chinese USA Flash Point 173.6±17.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Quinazoline antifolates thymidylate synthase inhibitors: lipophilic analogues with modification to the C2-methyl substituent.

J. Med. Chem. 39 , 695, (1996)

Modification of the potent thymidylate synthase (TS) inhibitor 1-[[N-[4-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N- prop-2-ynylamino]benzoyl]amino]methyl]-3-nitrobenzene (4a) has led to the synthesis of quinazolinone antifolates bearing function...

G.M.F. Visset et al.

J. Med. Chem. 35 , 659, (1992)