4-Methyl-5-acetyl thiazole
4-Methyl-5-acetyl thiazole structure
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Common Name | 4-Methyl-5-acetyl thiazole | ||
|---|---|---|---|---|
| CAS Number | 38205-55-9 | Molecular Weight | 141.191 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 228.6±20.0 °C at 760 mmHg | |
| Molecular Formula | C6H7NOS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 92.0±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Simultaneous quantitation of chlormethiazole and two of its metabolites in blood and plasma by gas--liquid chromatography.
J. Chromatogr. A. 182(1) , 55-62, (1980) A simple and rapid gas chromatographic method for the quantitation of chlormethiazole and two of its pharmacologically active metabolites, 5-acetyl-4-methylthiazole and 5-(1-hydroxyethyl)-4-methylthiazole, in plasma and blood is described. The total analysis ... |
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The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites.
Br. J. Pharmacol. 129(1) , 95-100, (2000) A single dose of clomethiazole (600 micromol kg(-1) i.p.) has previously been shown to be neuroprotective in the gerbil model of global ischaemia. In gerbils, clomethiazole (600 micromol kg(-1)) injection produced a rapid appearance (peak within 5 min) of dru... |
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