Phloridzin

Phloridzin Structure
Phloridzin structure
Common Name Phloridzin
CAS Number 7061-54-3 Molecular Weight 472.440
Density N/A Boiling Point 770ºC at 760 mmHg
Molecular Formula C21H28O12 Melting Point 113-114 °C(lit.)
MSDS Chinese USA Flash Point 270.7ºC
Symbol GHS07
GHS07
Signal Word Warning

Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice.

FASEB J. 29 , 3537-48, (2015)

Adipose tissue macrophages (ATMs) play an important role in the pathogenesis of obese type 2 diabetes. High-fat diet (HFD)-induced obesity has been shown to lead to ATM accumulation in rodents; however, the impact of hyperglycemia on ATM dynamics in HFD-fed t...

Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin.

Proc. Natl. Acad. Sci. U. S. A. 106 , 10638-43, (2009)

Adjustable control of therapeutic transgenes in engineered cell implants after transdermal and topical delivery of nontoxic trigger molecules would increase convenience, patient compliance, and elimination of hepatic first-pass effect in future therapies. Pse...