2-Chloro-5-ethylpyrimidine

2-Chloro-5-ethylpyrimidine Structure
2-Chloro-5-ethylpyrimidine structure
Common Name 2-Chloro-5-ethylpyrimidine
CAS Number 111196-81-7 Molecular Weight 142.586
Density 1.2±0.1 g/cm3 Boiling Point 249.4±9.0 °C at 760 mmHg
Molecular Formula C6H7ClN2 Melting Point 18°C
MSDS Chinese USA Flash Point 128.7±4.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Effects of various bases on acid-catalyzed amination of 2-chloro-5-ethylpyrimidine: synthesis of PPARpan agonist GW693085.

J. Org. Chem. 75(11) , 3904-7, (2010)

A unique buffering effect of various bases, i-Pr(2)NEt and CaCO(3) in particular, was observed for the acid-catalyzed chloro displacement of 2-chloro-5-ethylpyrimidine with a 2-methyl-2-phenylpropanamine. The use of the carefully chosen bases was essential fo...

239. The Dimroth rearrangement. Part I. Some alkylated 2-iminopyrimidines. Brown DJ and Harper JS.

J. Chem. Soc. , 1276-84, (1963)