PERFLUOROOCTYL BROMIDE
PERFLUOROOCTYL BROMIDE structure
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Common Name | PERFLUOROOCTYL BROMIDE | ||
|---|---|---|---|---|
| CAS Number | 423-55-2 | Molecular Weight | 498.96200 | |
| Density | 1.93 g/mL at 25 °C(lit.) | Boiling Point | 142 °C(lit.) | |
| Molecular Formula | C8BrF17 | Melting Point | 6 °C | |
| MSDS | Chinese USA | Flash Point | 141-143°C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Surfactant and perfluorocarbon aerosolization by means of inhalation catheters for the treatment of respiratory distress syndrome: an in vitro study.
J. Aerosol Med. Pulm. Drug Deliv. 24(2) , 81-7, (2011) The aerosolization of perfluorocarbons or surfactant has emerged as a feasible alternative to instillation, for the treatment of experimental respiratory distress syndrome. However, the biophysical properties that make these compounds useful in such therapies... |
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Optimization of perfluoro nano-scale emulsions: The importance of particle size for enhanced oxygen transfer in biomedical applications
Colloids Surf. B Biointerfaces 98 , 26-35, (2012) Graphical abstract |
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Rayleigh theory of ultrasound scattering applied to liquid-filled contrast nanoparticles.
Phys. Med. Biol. 55(11) , 3061-76, (2010) We present a novel modified theory based upon Rayleigh scattering of ultrasound from composite nanoparticles with a liquid core and solid shell. We derive closed form solutions to the scattering cross-section and have applied this model to an ultrasound contr... |
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Detection of fluorine labeled herceptin using cellular (19)F MRI ex vivo.
J. Pharm. Biomed. Anal. 51(4) , 894-900, (2010) The aim of this study was to assess the herceptin efficacy in ex vivo cultures of MCF-7 breast carcinoma cells. Herceptin was used with perfluorooctyl bromide (PFOB) and conjugated with lipoplex, containing plasmid DNA and lipofectamine (LipA), to allow fluor... |
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19F molecular MR imaging for detection of brain tumor angiogenesis: in vivo validation using targeted PFOB nanoparticles.
Angiogenesis 16(1) , 171-9, (2013) Molecular imaging with magnetic resonance imaging (MRI) targeted contrast agents has emerged as a promising diagnostic approach in cancer research to detect associated biomarkers. In this work, the potential of (19)F MRI was investigated to detect angiogenesi... |
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The role of hypoxia in canine cancer.
Vet. Comp. Oncol. 6(4) , 213-23, (2008) Human oncology has clearly demonstrated the existence of hypoxic tumours and the problematic nature of those tumours. Hypoxia is a significant problem in the treatment of all types of solid tumours and a common reason for treatment failure. Hypoxia is a negat... |
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Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations.
J. Phys. Chem. B 114(31) , 10086-96, (2010) Perfluorocarbon-based nanoemulsion particles have arisen as promising platforms for the cellular delivery of imaging and therapeutic agents to specific targets. However, current knowledge of the agent delivery mechanism is limited to qualitative and phenomeno... |
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Inhalation of nebulized perfluorochemical enhances recombinant adenovirus and adeno-associated virus-mediated gene expression in lung epithelium.
Hum. Gene Ther. Methods 23(2) , 98-110, (2012) Use of perfluorochemical liquids during intratracheal vector administration enhances recombinant adenovirus and adeno-associated virus (AAV)-mediated lung epithelial gene expression. We hypothesized that inhalation of nebulized perfluorochemical vapor would a... |
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Automation process for morphometric analysis of volumetric CT data from pulmonary vasculature in rats.
Comput. Methods Programs Biomed. 97(1) , 62-77, (2010) With advances in medical imaging scanners, it has become commonplace to generate large multidimensional datasets. These datasets require tools for a rapid, thorough analysis. To address this need, we have developed an automated algorithm for morphometric anal... |
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Regional overdistension identified with electrical impedance tomography in the perflubron-treated lung.
Physiol. Meas. 31(8) , S85-95, (2010) Regional lung overdistension occurring during high frequency oscillatory ventilation (HFOV) and partial liquid ventilation (PLV) was investigated in a prospective animal trial using 18 mechanically ventilated Yorkshire swine under general anesthesia. Lung inj... |