Di-methylsulfide borane
Di-methylsulfide borane structure
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Common Name | Di-methylsulfide borane | ||
|---|---|---|---|---|
| CAS Number | 13292-87-0 | Molecular Weight | 75.969 | |
| Density | 1.287 g/mL at 25 °C | Boiling Point | ~34 °C | |
| Molecular Formula | C2H9BS | Melting Point | -40--37°C | |
| MSDS | Chinese USA | Flash Point | 65 °F | |
| Symbol |
GHS02, GHS05, GHS07 |
Signal Word | Danger | |
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The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
Sci. Signal. 8 , ra82, (2015) Most patients with BRAF-mutant metastatic melanoma display remarkable but incomplete and short-lived responses to inhibitors of the BRAF kinase or the mitogen-activated protein kinase kinase (MEK), collectively BRAF/MEK inhibitors. We found that inherent resi... |
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[Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides].
Rev. Bras. Reumatol. 55 , 281-309, (2015) The treatment of autoimmune rheumatic diseases has gradually improved over the last half century, which has been expanded with the contribution of biological therapies or immunobiopharmaceuticals. However, we must be alert to the possibilities of undesirable ... |
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Nat. Commun. 5 , 5712, (2014) Increased expression of the Microphthalmia-associated transcription factor (MITF) contributes to melanoma progression and resistance to BRAF pathway inhibition. Here we show that the lack of MITF is associated with more severe resistance to a range of inhibit... |
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The Minor Allele of rs7574865 in the STAT4 Gene Is Associated with Increased mRNA and Protein Expression.
PLoS ONE 10 , e0142683, (2015) The T allele of rs7574865 in STAT4 confers risk of developing autoimmune disorders. However, its functional significance remains unclear. Here we analyze how rs7574865 affects the transcription of STAT4 and its protein expression.We studied 201 patients (80% ... |
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Age decreases macrophage IL-10 expression: Implications for functional recovery and tissue repair in spinal cord injury.
Exp. Neurol. 273 , 83-91, (2015) Macrophages with different activation states are present after spinal cord injury (SCI). M1 macrophages purportedly promote secondary injury processes while M2 cells support axon growth. The average age at the time of SCI has increased in recent decades, howe... |
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Preclinical Pharmacokinetics and In Vitro Metabolism of Asunaprevir (BMS-650032), a Potent Hepatitis C Virus NS3 Protease Inhibitor.
J. Pharm. Sci. 104 , 2813-23, (2015) Asunaprevir (ASV; BMS-650032), a low nanomolar inhibitor of the hepatitis C virus (HCV) NS3 protease, is currently under development, in combination with other direct-acting antiviral (DAA) agents for the treatment of chronic HCV infection. Extensive nonclini... |
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Challenges and solutions in the bioanalysis of BMS-986094 and its metabolites including a highly polar, active nucleoside triphosphate in plasma and tissues using LC-MS/MS.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1000 , 29-40, (2015) BMS-986094, a nucleotide polymerase inhibitor of the hepatitis C virus, was withdrawn from clinical trials because of a serious safety issue. To investigate a potential association between drug/metabolite exposure and toxicity in evaluations conducted after t... |
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Rivaroxaban and apixaban in orthopaedics: is there a difference in their plasma concentrations and anticoagulant effects?
Blood Coagul. Fibrinolysis 26 , 925-33, (2015) The aim of this study was to improve knowledge of what happens in the coagulation of orthopaedic patients under rivaroxaban and apixaban, in order to finalize and cross-validate effective measurement methods and to provide arguments for helping to reference o... |
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Novel solvates M(BH₄)₃S(CH₃)₂ and properties of halide-free M(BH₄)₃ (M = Y or Gd).
Dalton Trans. 43(35) , 13333-42, (2014) Rare earth metal borohydrides have been proposed as materials for solid-state hydrogen storage because of their reasonably low temperature of decomposition. New synthesis methods, which provide halide-free yttrium and gadolinium borohydride, are presented usi... |
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Safety and efficacy of abciximab in older adults undergoing percutaneous coronary intervention.
Int. J. Clin. Pract. 69 , 1334-40, (2015) As a result of increased cost and bleeding concerns, older patients receive abciximab during percutaneous coronary intervention (PCI) less often than younger patients.The aim of this was to evaluate the safety and efficacy of abciximab in older adults undergo... |