m-Xylylenediamine

m-Xylylenediamine Structure
m-Xylylenediamine structure
Common Name m-Xylylenediamine
CAS Number 1477-55-0 Molecular Weight 136.194
Density 1.1±0.1 g/cm3 Boiling Point 247.0±0.0 °C at 760 mmHg
Molecular Formula C8H12N2 Melting Point 14°C
MSDS Chinese USA Flash Point 130.4±21.3 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Prick testing with chemicals in the diagnosis of occupational contact urticaria and respiratory diseases.

Contact Dermatitis 72(1) , 20-32, (2014)

Little is known about the use of prick tests with chemicals in diagnosing occupational diseases.To evaluate the use of prick tests in the diagnosis of occupational contact urticaria, asthma and rhinitis caused by chemicals (undertaken at the Finnish Institute...

New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking.

J. Med. Chem. 49 , 6197-208, (2006)

Structure activity relationships for semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1) were studied using a library of arylalkylamine substrates, with the aim of contributing to the discovery of more efficient SSAO substrates. Exp...

Oxidative DNA cleavage promoted by multinuclear copper complexes: activity dependence on the complex structure.

Chemistry 12(25) , 6621-9, (2006)

Polynuclear copper complexes with two or three Cu(BPA) (BPA, bis(2-pyridylmethyl)amine) motifs, [Cu2(mTPXA)Cl4]3 H2O (1), [Cu2(pTPXA)Cl4]3 H2O (2), [Cu3(HPTAB)Cl5]Cl3 H2O (3) (mTPXA = N,N,N',N'-tetra-(2-pyridylmethyl)-m-xylylene diamine; pTPXA = N,N, N',N'-te...

An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002.

Contact Dermatitis 51(5-6) , 263-72, (2004)

Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. Sensitization occurs not only to the resins, but also to hardeners and reactive diluents. However, only a fraction of the ERS components currently in use are availabl...

Overall migration and specific migration of bisphenol A diglycidyl ether monomer and m-xylylenediamine hardener from an optimized epoxy-amine formulation into water-based food simulants.

Food Addit. Contam. 10(5) , 555-65, (1993)

The overall and specific migrations of BADGE n = 0 monomer and m-XDA hardener from a BEPOX LAB 889 (Gairesa internal code), epoxy system cured at room temperature, into three water-based food simulants are studied. Hydrolysis of BADGE n = 0 was observed in al...

[Allergic contact eczema caused by m-xylylene-diamine in the polyurethane silk production].

Derm. Beruf Umwelt. 38(4) , 117-20, (1990)

We found m-xylylene diamine, a widespread additive in plastics, to be a very potent sensitizer. Patch tests with other diamines revealed in all four patients allergic cross reactions to benzylamine. Two persons had also acquired an additional allergy to ethyl...

Binding of cationic bis-porphyrins linked with p- or m-xylylenediamine and their zinc(II) complexes to duplex DNA.

Molecules 13(12) , 3117-28, (2008)

Spectroscopic, viscometric, and molecular docking analysis of binding of cationic bis-porphyrins linked with p- or m-xylylenediamine (H(2)pXy and H(2)mXy) and their zinc(II) complexes (ZnpXy and ZnmXy) to duplex DNA are described. H(2)pXy and H(2)mXy bound to...

Dibasic inhibitors of human mast cell tryptase. Part 1: synthesis and optimization of a novel class of inhibitors.

Bioorg. Med. Chem. Lett. 10(20) , 2357-60, (2000)

The synthesis and optimization of a novel class of reversible and active-site directed dibasic inhibitors of human mast cell tryptase are described. The compounds were shown to be both remarkably potent and selective for tryptase with Ki values for optimized ...

Occupational contact dermatitis due to the epoxy hardener m-xylylenediamine.

Contact Dermatitis 44(6) , 374, (2001)

Design, synthesis, and biological evaluation of glycine-based molecular tongs as inhibitors of Abeta1-40 aggregation in vitro.

Bioorg. Med. Chem. 16(9) , 4810-22, (2008)

A series of N-terminus benzamides of glycine-based symmetric peptides, linked to m-xylylenediamine and 3,4'-oxydianiline spacers, were prepared and tested as inhibitors of beta-amyloid peptide Abeta(1-40) aggregation in vitro. Compounds with good anti-aggrega...