3-Methoxy-2-phenylethylamine
3-Methoxy-2-phenylethylamine structure
|
Common Name | 3-Methoxy-2-phenylethylamine | ||
|---|---|---|---|---|
| CAS Number | 2039-67-0 | Molecular Weight | 151.206 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 262.7±0.0 °C at 760 mmHg | |
| Molecular Formula | C9H13NO | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 104.9±13.6 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
|
Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis.
Biochemistry 40 , 14215, (2001) Cytochrome P450 (P450) 2D6 oxidizes a wide variety of drugs typically at a distance of 5-7 A from a basic nitrogen on the substrate. To investigate the determinants of P450 2D6 catalysis, we analyzed the binding and oxidation of phenethylamine substrates. P45... |
|
|
A microdialysis study on striatal dopamine, 5-HT and metabolites in conscious rats after various treatments: evidence for extravesicular release of dopamine.
Neuroreport 5(1) , 53-6, (1993) The effects of death and various treatments that affect the status of nigrostriatal neurones on striatal release of dopamine (DA) and 5-hydroxytryptamine (5-HT) and their metabolites 3,4-dihydroxyphenylacetic acid (DOPAC), 3-methoxy-4-hydroxyphenylethylamine ... |
|
|
Structure–activity correlations for β-phenethylamines at human trace amine receptor 1
Bioorg. Med. Chem. 16 , 7415-23, (2008) CoMFA 3D-QSAR studies on the potency of 68 β-phenethylamine analogs to activate hTAAR 1 (61% steric, 39% electrostatic) indicates that bulk both at nitrogen and 4-aryl leads to lower potency. |
|
|
Tetrahedron 62 , 9002, (2006)
|
|
|
Tetrahedron Lett. 48 , 835, (2007)
|