1-(2-Fluorophenyl)methanamine

1-(2-Fluorophenyl)methanamine Structure
1-(2-Fluorophenyl)methanamine structure
Common Name 1-(2-Fluorophenyl)methanamine
CAS Number 89-99-6 Molecular Weight 125.144
Density 1.1±0.1 g/cm3 Boiling Point 185.9±0.0 °C at 760 mmHg
Molecular Formula C7H8FN Melting Point N/A
MSDS Chinese USA Flash Point 67.2±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

Bioorg. Med. Chem. Lett. 17 , 2171-2178, (2007)

The design, synthesis, and SAR of a series of substituted spirohydantoins are described. Optimization of an in-house screening hit gave compounds that exhibited potent binding affinity and functional activity at MCH-R1.

9-(2-Fluorobenzyl)-6-(methylamino)-9H-purine hydrochloride. Synthesis and anticonvulsant activity.

J. Med. Chem. 29(7) , 1133-4, (1986)