hydrocodone bitartrate
hydrocodone bitartrate structure
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Common Name | hydrocodone bitartrate | ||
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| CAS Number | 143-71-5 | Molecular Weight | 449.45100 | |
| Density | N/A | Boiling Point | 461.4ºC at 760 mmHg | |
| Molecular Formula | C22H27NO9 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 232.9ºC | |
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Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats.
J. Pharmacol. Exp. Ther. 280 , 1374-1382, (1997) Humans that lack cytochrome P450 2D6 (CYP2D6) activity may have an altered risk of drug dependence or abuse because this enzyme is important in the metabolism of some drugs of abuse, including hydrocodone. In rats, hydrocodone conversion to hydromorphone is c... |
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Mu receptor binding of some commonly used opioids and their metabolites.
Life Sci. 48 , 2165-2171, (1991) The binding affinity to the mu receptor of some opioids chemically related to morphine and some of their metabolites was examined in rat brain homogenates with 3H-DAMGO. The chemical group at position 6 of the molecule had little effect on binding (e.g. morph... |
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The antitussive activity of delta-opioid receptor stimulation in guinea pigs.
J. Pharmacol. Exp. Ther. 292 , 803-809, (2000) In this study, the activity of the delta-opioid receptor subtype-selective agonist, SB 227122, was investigated in a guinea pig model of citric acid-induced cough. Parenteral administration of selective agonists of the delta-opioid receptor (SB 227122), mu-op... |