hydrocodone bitartrate

Modify Date: 2024-01-06 17:19:20

hydrocodone bitartrate Structure
hydrocodone bitartrate structure
Common Name hydrocodone bitartrate
CAS Number 143-71-5 Molecular Weight 449.45100
Density N/A Boiling Point 461.4ºC at 760 mmHg
Molecular Formula C22H27NO9 Melting Point N/A
MSDS USA Flash Point 232.9ºC

 Names

Name (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one,(2R,3R)-2,3-dihydroxybutanedioic acid
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 461.4ºC at 760 mmHg
Molecular Formula C22H27NO9
Molecular Weight 449.45100
Flash Point 232.9ºC
Exact Mass 449.16900
PSA 153.83000
Vapour Pressure 1.07E-08mmHg at 25°C
Storage condition 2-8°C
Water Solubility H2O: 62 mg/mL

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes F,T
Risk Phrases 23/25-36/38
Safety Phrases S7;S16;S24;S33;S45
RIDADR UN 1230 3/PG 2
WGK Germany 3

 Synthetic Route

~56%

hydrocodone bitartrate Structure

hydrocodone bit...

CAS#:143-71-5

Literature: ZENTIVA, A.S. Patent: WO2005/100361 A1, 2005 ; Location in patent: Page/Page column 5-6 ;

 Precursor & DownStream

Precursor  2

DownStream  1

 Articles3

More Articles
Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats.

J. Pharmacol. Exp. Ther. 280 , 1374-1382, (1997)

Humans that lack cytochrome P450 2D6 (CYP2D6) activity may have an altered risk of drug dependence or abuse because this enzyme is important in the metabolism of some drugs of abuse, including hydroco...

Mu receptor binding of some commonly used opioids and their metabolites.

Life Sci. 48 , 2165-2171, (1991)

The binding affinity to the mu receptor of some opioids chemically related to morphine and some of their metabolites was examined in rat brain homogenates with 3H-DAMGO. The chemical group at position...

The antitussive activity of delta-opioid receptor stimulation in guinea pigs.

J. Pharmacol. Exp. Ther. 292 , 803-809, (2000)

In this study, the activity of the delta-opioid receptor subtype-selective agonist, SB 227122, was investigated in a guinea pig model of citric acid-induced cough. Parenteral administration of selecti...

 Synonyms

Robidone
EINECS 205-608-1
Synkonin
MFCD00078557
Codone
Dicotrate
Dicodrine
Dicodethal
Stodcodon
Biocodone
4,5-epoxy-3-methoxy-17-methylmorphinan-6-one bitartrate
Hycon
hydrocodone ditartrate
Hydrokon