Bromhexine hydrochloride

Bromhexine hydrochloride Structure
Bromhexine hydrochloride structure
Common Name Bromhexine hydrochloride
CAS Number 611-75-6 Molecular Weight 412.591
Density N/A Boiling Point 441.5ºC at 760 mmHg
Molecular Formula C14H21Br2ClN2 Melting Point 240-244 °C
MSDS Chinese USA Flash Point 220.8ºC

Investigation of internal structure of fine granules by microtomography using synchrotron X-ray radiation.

Int. J. Pharm. 445(1-2) , 93-8, (2013)

Computed tomography (CT) using synchrotron X-ray radiation was evaluated as a non-destructive structural analysis method for fine granules. Two kinds of granules have been investigated: a bromhexine hydrochloride (BHX)-layered Celphere CP-102 granule coated w...

Structural changes of polymer-coated microgranules and excipients on tableting investigated by microtomography using synchrotron X-ray radiation.

Int. J. Pharm. 481(1-2) , 132-9, (2015)

Multiple-unit tablets consisting of polymer-coated microgranules and excipients have a number of advantageous pharmaceutical properties. Polymer-coated microgranules are known to often lose their functionality because of damage to the polymer coating caused b...

Predicting prognosis in idiopathic pulmonary fibrosis.

Sarcoidosis Vasc. Diffuse Lung Dis. 27(2) , 85-95, (2010)

Idiopathic pulmonary fibrosis (IPF) is a parenchymal lung disease characterized by progressive interstitial fibrosis. In 2002, the ATS/ERS published new criteria that significantly changed the definition of IPF, resulting in a more homogeneous group of patien...

Contaminations of herbal products determined by NMR fingerprint.

Nat. Prod. Res. 24(14) , 1325-9, (2010)

The utilisation of NMR fingerprinting is proposed as a rapid, available and reliable method to determine the contamination of herbal products. The presence of nimesulide has been reported recently as the contaminant of P.C. 28 Plus, a product based on herbal ...

Superior mesenteric artery aneurysm: importance of sonography as the primary imaging technique for detection.

J. Ultrasound Med. 29(10) , 1503-6, (2010)

Solubility and solution stability studies of different amino acid prodrugs of bromhexine.

Drug Dev. Ind. Pharm. 38(11) , 1319-27, (2012)

The aim of the present study was to prepare the amino acid prodrugs of bromhexine hydrochloride to improve its solubility.All the prodrugs were synthesized by first reacting bromhexine with tert-butoxycarbonyl (Boc) protected amino acid and then deprotection ...

Diffuse lung disease in children.

Pediatr. Ann. 39(12) , 777-83, (2010)

[Comparative analysis of linear morphometric parameters of the humane mandibula obtained by direct and indirect measurement].

Vojnosanit. Pregl. 67(10) , 839-46, (2010)

Reconstruction of lost, damaged or distorted mandibular bone presents a challenge from the functional side, as well as from the esthetic point of view. The aim of this study was to determinate potential differences between values of the basic linear moprhomet...

Le syndrome de Goujerot-Sjögren juvénile : à propos de 3 cas

Arch. Pediatr. 17(11) , 1531-4, (2010)

Le syndrome de Gougerot-Sjögren (SGS) est une affection rare chez l’enfant. Le diagnostic chez l’adulte est basé sur des critères cliniques, immunologiques et histopathologiques. Les manifestations cliniques sont différentes chez l’enfant. Nous rapportons 3 c...

[Use of the mucoregulator ascoril for respiratory diseases].

Ter. Arkh. 84(10) , 86-90, (2012)

The paper deals with the use of the combined mucoregulatory drug ascoril in pulmonological care. Due to its multicomponent composition, the drug has mucoregulatory properties that combine a bronchodilator effect and an ability to dilute sputum and to synthesi...