Adenosine 5′-[β-thio]diphosphate trilithium salt
![Adenosine 5′-[β-thio]diphosphate trilithium salt Structure](https://image.chemsrc.com/caspic/297/73536-95-5.png)
Adenosine 5′-[β-thio]diphosphate trilithium salt structure
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Common Name | Adenosine 5′-[β-thio]diphosphate trilithium salt | ||
|---|---|---|---|---|
| CAS Number | 73536-95-5 | Molecular Weight | 461.066 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H12Li3N5O9P2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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Both the stimulation and inhibition of root hair growth induced by extracellular nucleotides in Arabidopsis are mediated by nitric oxide and reactive oxygen species.
Plant Mol. Biol. 74(4-5) , 423-35, (2010) Root hairs secrete ATP as they grow, and extracellular ATP and ADP can trigger signaling pathways that regulate plant cell growth. In several plant tissues the level of extracellular nucleotides is limited in part by ectoapyrases (ecto-NTPDases), and the grow... |
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Expression of purinergic P2Y receptor subtypes by INS-1 insulinoma beta-cells: a molecular and binding characterization.
Eur. J. Pharmacol. 568(1-3) , 54-60, (2007) Purinergic P2Y-receptor agonists amplify glucose-induced insulin secretion from pancreatic beta-cells, thus offering new opportunities for the treatment of type 2 diabetes. However, little is known about which subtypes of purinergic P2Y receptors are expresse... |
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Desensitization of endothelial P2Y1 receptors by PKC-dependent mechanisms in pressurized rat small mesenteric arteries.
Br. J. Pharmacol. 158(6) , 1609-20, (2009) Extracellular nucleotides play a crucial role in the regulation of vascular tone and blood flow. Stimulation of endothelial cell P2Y1 receptors evokes concentration-dependent full dilatation of resistance arteries. However, this GPCR can desensitize upon prol... |
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Coordinate pathways for nucleotide and EGF signaling in cultured adult neural progenitor cells.
J. Cell Sci. 122(Pt 14) , 2524-33, (2009) The adult subventricular zone (SVZ) contains astrocyte-like stem cells capable of generating new neurons for the olfactory bulb. Adult neurogenesis is driven by a variety of signal systems that can induce synergistic or opposing cellular responses. It is ther... |
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Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter.
Am. J. Physiol. Gastrointest. Liver Physiol. 294(4) , G1041-51, (2008) The neurotransmitter(s) underlying nitric oxide synthase (NOS)-independent neural inhibition in the internal anal sphincter (IAS) is still uncertain. The present study investigated the role of purinergic transmission. Contractile and electrical responses to e... |
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P2Y1 receptor-mediated glutamate release from cultured dorsal spinal cord astrocytes.
J. Neurochem. 106(5) , 2106-18, (2008) P2 receptors have been implicated in the release of neurotransmitter and proinflammatory cytokines by the response to neuroexcitatory substances in astrocytes. In the present study, we examined the mechanisms of ADP and adenosine 5'-O-2-thiodiphosphate (ADPbe... |
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P2 receptor-mediated signaling in spherical bushy cells of the mammalian cochlear nucleus.
J. Neurophysiol. 102(3) , 1821-33, (2009) Purinoreceptors of the P2 family contribute strongly to signaling in the cochlea, but little is known about the effects of purinergic neurotransmission in the central auditory system. Here we examine P2 receptor-mediated signaling in the large spherical bushy... |
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Activation of P2Y receptors by ATP and by its analogue, ADPbetaS, triggers two calcium signal pathways in the longitudinal muscle of mouse distal colon.
Eur. J. Pharmacol. 595(1-3) , 84-9, (2008) Our previous research showed that ATP and adenosine 5'-O-2-thiodiphosphate (ADPbetaS) induce contractile effects in the longitudinal muscle of mouse distal colon via activation of P2Y receptors which are not P2Y(1) or P2Y(12) subtypes. This study investigated... |
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Purinergic signals regulate daily S-phase cell activity in the ciliary marginal zone of the zebrafish retina.
J. Biol. Rhythms 26(2) , 107-17, (2011) Regeneration and growth that occur in the adult teleost retina have been helpful in identifying molecular and cellular mechanisms underlying cell proliferation and differentiation. Here, it is reported that S-phase cell number, in the ciliary marginal zone (C... |
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Opposite modulation of astroglial proliferation by adenosine 5'-O-(2-thio)-diphosphate and 2-methylthioadenosine-5'-diphosphate: mechanisms involved.
Neuroscience 182 , 32-42, (2011) The contribution of P2Y(12,13) receptors to astroglial proliferation was investigated by testing the effects of two agonists with high affinity for these receptors, adenosine 5'-O-(2-thio)-diphosphate (ADPβS) and 2-methylthioadenosine-5'-diphosphate (2-MeSADP... |