5-Fluoro-2-nitroaniline
5-Fluoro-2-nitroaniline structure
|
Common Name | 5-Fluoro-2-nitroaniline | ||
|---|---|---|---|---|
| CAS Number | 2369-11-1 | Molecular Weight | 156.115 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 295.5±20.0 °C at 760 mmHg | |
| Molecular Formula | C6H5FN2O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 132.5±21.8 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
|
Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreductively activated, hypoxia-selective DNA-oxidizing agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
J. Org. Chem. 79(16) , 7520-31, (2014) Tirapazamine (3-amino-1,2,4-benzotriazine 1,4-dioxide) is a heterocyclic di-N-oxide that undergoes enzymatic deoxygenation selectively in the oxygen-poor (hypoxic) cells found in solid tumors to generate a mono-N-oxide metabolite. This work explored the idea ... |
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