3,5-Dichloro-2-hydroxybenzoic acid

3,5-Dichloro-2-hydroxybenzoic acid Structure
3,5-Dichloro-2-hydroxybenzoic acid structure
Common Name 3,5-Dichloro-2-hydroxybenzoic acid
CAS Number 320-72-9 Molecular Weight 207.011
Density 1.7±0.1 g/cm3 Boiling Point 319.3±42.0 °C at 760 mmHg
Molecular Formula C7H4Cl2O3 Melting Point 221-224 °C
MSDS Chinese USA Flash Point 146.9±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Spectral deciphering of the interaction between an intramolecular hydrogen bonded ESIPT drug, 3,5-dichlorosalicylic acid, and a model transport protein.

Phys. Chem. Chem. Phys. 14(25) , 8892-902, (2012)

The present work demonstrates a detailed characterization of the interaction of a bio-active drug molecule 3,5-dichlorosalicyclic acid (3,5DCSA) with a model transport protein Bovine Serum Albumin (BSA). The drug molecule is a potential candidate exhibiting E...

Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: implications for inhibitor binding and selectivity.

Arch. Biochem. Biophys. 479(1) , 82-7, (2008)

The structure of aldehyde reductase (ALR1) in ternary complex with the coenzyme NADPH and 3,5-dichlorosalicylic acid (DCL), a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1), was determined at a resolution of 2.41A. The inhibitor forme...