Sodium ethylenesulphonate

Sodium ethylenesulphonate Structure
Sodium ethylenesulphonate structure
Common Name Sodium ethylenesulphonate
CAS Number 3039-83-6 Molecular Weight 130.098
Density 1.176 g/mL at 25 °C Boiling Point N/A
Molecular Formula C2H3NaO3S Melting Point -20 °C
MSDS Chinese Flash Point N/A

A potent specific inhibitor of 6-phosphogluconate dehydrogenase of Cryptococcus neoformans and of certain other fungal enzymes.

Mycopathologia 123(3) , 155-158, (1993)

A particular lot of the zwitterionic buffer, 2(N-morpholino) ethane sulfonic acid (MES), contained a contaminant that inhibited a number of fungal NADP-dependent dehydrogenases. Enzymes that were particularly sensitive include 6-phosphogluconate dehydrogenase...

Synthesis, characterization and applications of graft copolymer (κ-carrageenan-g-vinylsulfonic acid).

Int. J. Biol. Macromol. 50(3) , 826-32, (2012)

The synthesis of graft copolymer (κ-carrageenan-g-vinylsulfonic acid) is carried out in nitrogen atmosphere using potassium peroxymonosulfate (PMS) and malonic acid (MA) as redox system. The effect of reaction variables including the concentration of vinylsul...

A new route to sulfonamides via intermolecular radical addition to pentafluorophenyl vinylsulfonate and subsequent aminolysis.

Org. Lett. 4(15) , 2549-51, (2002)

[reaction: see text] Various radical species generated from either the corresponding iodo- or bromo- compounds and tri-n-butyltin hydride were added in an intermolecular fashion to the activated acceptor pentafluorophenyl vinylsulfonate. The products of each ...

Capillary electrochromatography with polyacrylamide monolithic stationary phases having bonded dodecyl ligands and sulfonic acid groups: evaluation of column performance with alkyl phenyl ketones and neutral moderately polar pesticides.

Electrophoresis 22(12) , 2593-9, (2001)

In this report, we describe the preparation of porous polyacrylamide-based monolithic columns via vinyl polymerization. These monoliths possess in their structures bonded dodecyl ligands and sulfonic acid groups. While the sulfonic acid groups are meant to su...

Development of monolithic enzymatic reactors in glass microchips for the quantitative determination of enzyme substrates using the example of glucose determination via immobilized glucose oxidase.

Electrophoresis 26(12) , 2303-12, (2005)

A one-step procedure for the immobilization of glucose oxidase in fused-silica capillaries and in glass microchips was developed based on enzyme entrapment in a polyacrylamide-based monolithic column. The inner capillary surface was silanized with gamma-metha...

Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid).

J. Biol. Chem. 278(23) , 20934-8, (2003)

Ribonuclease A (RNase A) can make multiple contacts with an RNA substrate. In particular, the enzymatic active site and adjacent subsites bind sequential phosphoryl groups in the RNA backbone through Coulombic interactions. Here, oligomers of vinylsulfonic ac...

Apatite formation abilities and mechanical properties of hydroxyethylmethacrylate-based organic-inorganic hybrids incorporated with sulfonic groups and calcium ions.

J. Mater. Sci. Mater. Med. 20(1) , 157-61, (2009)

Apatite formation in the living body is an essential requirement for artificial materials to exhibit bone-bonding bioactivity. It has been recently revealed that sulfonic groups trigger apatite nucleation in a body environment. Organic-inorganic hybrids consi...

The role of vinyl sulfonic acid homopolymer in calcium oxalate crystallization.

Colloids Surf. B Biointerfaces 78(2) , 357-62, (2010)

In this study, the effect of water soluble homopolymer of vinylsulfonic acid on spontaneous crystallization of calcium oxalate (CaOx) was investigated. CaOx crystals exhibiting different shapes and phase structures were produced in the presence of polymer. Wh...

Investigation of the ion-exchange properties of methacrylate-based mixed-mode monolithic stationary phases employed as stationary phases in capillary electrochromatography.

J. Chromatogr. A. 1160(1-2) , 326-35, (2007)

The potential of methacrylate-based mixed-mode monolithic stationary phases bearing sulfonic acid groups for the separation of positively charged analytes (alkylanilines, amino acids, and peptides) by capillary electrochromatography (CEC) is investigated. The...

Potency and selectivity of P2/P3-modified inhibitors of cysteine proteases from trypanosomes.

Bioorg. Med. Chem. Lett. 18(2) , 624-8, (2008)

A systematic study of P2 and P3 substitution in a series of vinyl sulfone cysteine protease inhibitors is described. The introduction of a methyl substituent in the P2 phenylalanine aryl ring had a favorable effect on protease inhibition and conferred modest ...