Robenidine hydrochloride
Robenidine hydrochloride structure
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Common Name | Robenidine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 25875-50-7 | Molecular Weight | 370.664 | |
| Density | N/A | Boiling Point | 488.1ºC at 760 mmHg | |
| Molecular Formula | C15H14Cl3N5 | Melting Point | 252-254°C | |
| MSDS | Chinese USA | Flash Point | 249ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Effect of subcutaneously administered diclazuril on the output of Eimeria species oocysts by experimentally infected rabbits.
Vet. Rec. 162(5) , 153-5, (2008) The effect of subcutaneously injected diclazuril on the output of Eimeria species oocysts was studied in experimentally infected rabbits. Diclazuril was administered either prophylactically at 0.5, 1 or 2 mg/kg bodyweight two days before each rabbit was inocu... |
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Use of antigen mimics to produce specific antibodies to anti-coccidial drugs.
J. Immunol. Methods 323(1) , 31-8, (2007) A range of polyclonal antibodies was successfully produced to the coccidiostatic drugs diclazuril and robenidine. Initial attempts to make immunogenic complexes of both drugs were ineffective due to difficulties encountered while trying to couple the compound... |
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Sensitivity of field isolates of Eimeria tenella to anticoccidial drugs in the chicken.
Res. Vet. Sci. 47(1) , 125-8, (1989) Thirty isolates of Eimeria tenella obtained from broiler and breeder farms were examined for their sensitivity to anticoccidial drugs. All were sensitive to robenidine, 28 were sensitive to methyl benzoquate, 25 to clopidol and 21 to nicarbazin. Most isolates... |
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Antileishmanial effect of a potent S-adenosylmethionine decarboxylase inhibitor: CGP 40215A.
Pharmacol. Res. 33(1) , 67-70, (1996) CGP 40215A, specific S-adenosylmethionine decarboxylase (AdoMetDC) inhibitor was found to inhibit the growth of Leishmania donovani promastigotes (strain UR6) in a dose-dependent manner with an IC50 of 18 microM. The growth inhibition was reversed with 100 mi... |
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Sensitivity of Escherichia coli O157:H7 strain 932 to selected anticoccidial drugs in broiler chicks.
Poult. Sci. 75(1) , 42-6, (1996) The ability of selected anticoccidial drugs to inhibit the colonization of day-old male broiler chicks (Cornish Rocks) by Escherichia coli O157:H7, strain 932 was examined. Chicks were challenged with 1.8 x 10(9) E. coli O157:H7 on Day 1, and fed diets supple... |
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Action of robenidine on the intestinal transport and digestion of nutrients in rabbit.
Eur. J. Pharmacol. 248(2) , 137-44, (1993) Robenidine is an anticoccidial guanidine used as an additive in rabbit fodder. Because its action is restricted to the small intestine, the present work addresses the question whether robenidine affects the growth of the animals, sugar and amino acid intestin... |
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Fetotoxicity of some anticoccidial drugs in chickens.
DTW Dtsch. Tierarztl. Wochenschr. 96(6) , 296-8, (1989) Fetotoxic effects induced by three anticoccidial drugs: robenidine, salinomycin and arprinocid were elucidated in the chicken. Different doses of these drugs were inoculated in groups of embryonated chicken eggs by the yolk sac route. After inoculation, candl... |
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In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga.
Drugs Exp. Clin. Res. 27(4) , 127-33, (2001) Treatment with the drugs berenil, dibromopropamidine, pentamidine and CGP-4O-215 were found to alter levels of intracellular polyamines of Acanthamoeba polyphagia trophozoites in organisms. While the polyamine, spermidine, consistently remained higher in the ... |
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Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase.
Biochemistry 45(25) , 7797-807, (2006) S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoyl-dependent enzyme that catalyzes an essential step in polyamine biosynthesis. The polyamines are required for cell growth, and the biosynthetic enzymes are targets for antiproliferative drugs. The fun... |
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The effects of shuttle programs upon the growth of broilers and the development of immunity to eimeria species.
Poult. Sci. 72(4) , 658-63, (1993) A floor-pen trial was conducted to investigate the effects of different shuttle programs upon the growth of broilers to 8 wk of age. Nicarbazin, halofuginone, and robenidine, when included in the starter feed for 3 wk, were effective in preventing lesions due... |