Boc-Gly-OH
Boc-Gly-OH structure
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Common Name | Boc-Gly-OH | ||
|---|---|---|---|---|
| CAS Number | 4530-20-5 | Molecular Weight | 175.182 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 315.9±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H13NO4 | Melting Point | 86-89 °C(lit.) | |
| MSDS | USA | Flash Point | 144.9±23.2 °C | |
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In situ fabrication of cleavable peptide arrays on polydimethylsiloxane and applications for kinase activity assays.
Anal. Chim. Acta 865 , 53-9, (2015) Polydimethylsiloxane (PDMS) is widely used for microfabrication and bioanalysis; however, its surface functionalization is limited due to the lack of active functional groups and incompatibility with many solvents. We presented a novel approach for in situ fa... |
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Accumulation of cell-penetrating peptides in large unilamellar vesicles: A straightforward screening assay for investigating the internalization mechanism.
Biopolymers 104 , 533-43, (2015) The internalization of cell-penetrating peptides (CPPs) into liposomes (large unilamellar vesicles, LUVs) was studied with a rapid and robust procedure based on the quenching of a small fluorescent probe, 7-nitrobenz-2-oxa-1,3-diazole (NBD). Quenching can be ... |
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Optimization of the Ugi reaction using parallel synthesis and automated liquid handling.
J. Vis. Exp. (21) , doi:10.3791/942, (2008) The optimization of a Ugi reaction involving the mixing of furfurylamine, benzaldehyde, boc-glycine and t-butylisocyanide is described. Triplicate runs of 48 parallel experiments are reported, varying concentration, solvent and the excess of some of the reage... |
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Efficient total synthesis of pulchellalactam, a CD45 protein tyrosine phosphatase inhibitor.
J. Org. Chem. 67(14) , 4702-6, (2002) A new approach to a CD45 protein tyrosine phosphatase inhibitor, pulchellalactam, is described. The key step of the sequence involves addition and elimination of an enolic lactam in a single step and 70% yield, employing an organocuprate reagent. The resultin... |
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Measurements of carbon to amide-proton distances by C-H dipolar recoupling with 15N NMR detection.
J. Am. Chem. Soc. 125(19) , 5648-9, (2003) A new magic-angle spinning NMR method for measuring internuclear distances between a 13C-labeled site and amide protons is described. The magnetization of the protons evolves under homonuclear decoupling and the recoupled 13C-1H dipolar interaction, which pro... |
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15N spin diffusion rate in solid-state NMR of totally enriched proteins: the magic angle spinning frequency effect.
J. Magn. Reson. 182(2) , 339-42, (2006) As demonstrated by means of the one-dimensional solid-state MAS exchange experiment (CODEX), the rate of the proton driven spin diffusion between backbone (15)N nuclei in totally enriched protein depends strongly on the magic angle spinning (MAS) frequency: s... |
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Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration.
Neuroreport 5(7) , 777-80, (1994) Although glycine does not cross easily the blood-brain barrier, it exhibits at very high doses (10-40 mmol kg-1) a modest anticonvulsant activity. In this study, carbamate derivatives--N-benzyloxycarbonylglycine (Z-glycine) and N,tert-butoxycarbonylglycine (B... |
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Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).
Bioorg. Med. Chem. 16 , 10061-74, (2008) Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and ... |
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Metabolism of C-terminal pentapeptide of gastrin in the rat. Part IV. Catabolic pathways of the N-terminal BOC-14C-glycine fragment.
Hepatogastroenterology. 27(2) , 146-9, (1980) The catabolism of the 14C-labelled pentagastrin was investigated in rats. The following results were found: -- the labelled BOC-glycine fragment is split off the pentagastrin in the small intestine -- it is absorbed through the intestinal wall, and -- enters ... |