5-Bromo-2-iodotoluene

5-Bromo-2-iodotoluene Structure
5-Bromo-2-iodotoluene structure
Common Name 5-Bromo-2-iodotoluene
CAS Number 116632-39-4 Molecular Weight 296.931
Density 2.1±0.1 g/cm3 Boiling Point 264.2±20.0 °C at 760 mmHg
Molecular Formula C7H6BrI Melting Point N/A
MSDS Chinese USA Flash Point 113.6±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors.

J. Med. Chem. 58 , 6225-36, (2015)

On the basis of a crystal structure of a phenylpyrrolidine lead and subsequent molecular modeling results, we designed and synthesized a novel series of macrocyclic FVIIa inhibitors. The optimal 16-membered macrocycle was 60-fold more potent than an acyclic a...

A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers.

J. Med. Chem. 46 , 3514-3525, (2003)

The pathology of chronic dermal ulcers is characterized by excessive proteolytic activity which degrades extracellular matrix (required for cell migration) and growth factors and their receptors. The overexpression of MMP-3 (stromelysin-1) and MMP-13 (collage...

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Synthesis, Properties and Applications of Biphenyl Functionalized 9, 9-Bis (4-diphenylaminophenyl) fluorenes as Bifunctional Materials for Organic Electroluminescent Devices. Thangthong A-M, et al.

European J. Org. Chem. 27 , 5263-5274, (2012)

Synthesis of comb polyphenylenes by Suzuki coupling from AB macromonomers. Zhou S, et al.

J. Polym. Sci. A Polym. Chem. 52(11) , 1519-1524, (2014)