Azure A chloride

Azure A chloride Structure
Azure A chloride structure
Common Name Azure A chloride
CAS Number 531-53-3 Molecular Weight 291.80
Density N/A Boiling Point 442.8ºC at 760 mmHg
Molecular Formula C14H14ClN3S Melting Point 290 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 221.6ºC

A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009)

Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligomers and linear fibrils, which possess distinct biological ac...

Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.

Hum. Mol. Genet. 23(11) , 2953-67, (2014)

Mutations of Filamin genes, which encode actin-binding proteins, cause a wide range of congenital developmental malformations in humans, mainly skeletal abnormalities. However, the molecular mechanisms underlying Filamin functions in skeletal system formation...

Ligand polarizability contributes to tau fibril binding affinity.

Bioorg. Med. Chem. 19 , 5147-54, (2011)

Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer's disease. Diverse compounds with high affinity for tau aggregates have been reported from high-throughput screens, but th...

Effect of Excessive Potassium Iodide on Rat Aorta Endothelial Cells.

Biol. Trace Elem. Res. 166 , 201-9, (2015)

The aim of the current study was to investigate the effect of excess iodine on rat aorta endothelial cells and the potential underlying mechanisms. Rat aorta endothelial cells were cultured with iodide ion (3506, 4076, 4647, 5218, 5789, 6360, 6931, and 7512 m...

Grafted Azure A modified electrodes as disposable β-nicotinamide adenine dinucleotide sensors.

Anal. Chim. Acta 747 , 84-91, (2012)

We report the in situ generation of aryl diazonium cations of Azure A, a redox-active phenothiazine dye, by reaction between the corresponding aromatic aminophenyl group and sodium nitrite in 0.1 M HCl. The subsequent electrochemical reduction of these dye di...

Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis.

PLoS ONE 9(9) , e106976, (2014)

It is now well accepted that multipotent Bone-Marrow Mesenchymal Stem Cells (BM-MSC) contribute to cancer progression through several mechanisms including angiogenesis. However, their involvement during the lymphangiogenic process is poorly described. Using B...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

[Study on the mechanism of color changes of Azur A and sodium dodecyl sulphate before micelle formation].

Guang Pu Xue Yu Guang Pu Fen Xi 28(1) , 134-7, (2008)

The mechanism of color changes of sodium dodecyl sulphate(SDS) and Azur A (AA) before micelle formation was studied by spectral probe. The changes in the absorption spectra of SDS-AA and chondroitin sulfate(CS)-AA complexes were compared. The influence of eth...

[Study on the interaction between alginic sodium diester and azur A and the application].

Guang Pu Xue Yu Guang Pu Fen Xi 27(2) , 317-20, (2007)

The interaction of alginic sodium diester (ASD) and azur A (AA) was studied by absorption spectra. The influence of pH and the molar ratio of AA/ASD on the spectra was investigated. The maximum binding number (N = 168) and the binding equilibrium constant (K ...

Melanin synthesis by Sclerotinia sclerotiorum.

Mycologia 101(3) , 296-304, (2009)

We confirmed that the melanin produced by Sclerotinia sclerotiorum is a dihydroxynaphthalene (DHN). The specific DHN melanogenesis inhibitor test that uses tricyclazole at low levels (typically 2-5 ppm) to cause a confirmatory appearance of soluble red-brown ...