C2-8

C2-8 Structure
C2-8 structure
Common Name C2-8
CAS Number 300670-16-0 Molecular Weight 510.19900
Density N/A Boiling Point N/A
Molecular Formula C19H14Br2N2O3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.

Proc. Natl. Acad. Sci. U. S. A. 102 , 892-897, (2005)

Polyglutamine (polyQ) disorders, including Huntington's disease (HD), are caused by expansion of polyQ-encoding repeats within otherwise unrelated gene products. In polyQ diseases, the pathology and death of affected neurons are associated with the accumulati...