2-Hydroxyethyl salicylate

2-Hydroxyethyl salicylate Structure
2-Hydroxyethyl salicylate structure
Common Name 2-Hydroxyethyl salicylate
CAS Number 87-28-5 Molecular Weight 182.173
Density 1.3±0.1 g/cm3 Boiling Point 294.3±0.0 °C at 760 mmHg
Molecular Formula C9H10O4 Melting Point 25°C
MSDS USA Flash Point 128.3±15.8 °C
Symbol GHS07
GHS07
Signal Word Warning

[On interactions of drugs on and in the skin/comparative studies on the mutual influences of ethyleneglycol-monosalicylate and benzylnicotinate (author's transl)].

Derm. Beruf Umwelt. 29(6) , 161-7, (1981)

Three radioactively marked substances (on the basis of a carbopol gel, 80% water - isopropanol) were analyzed comparatively in regard to the penetration of ethyleneglycolmonosalicylate and benzylnicotinate to intact and impaired human skin. The objective of t...

[Therapy of rheumatic disease with a hydroxyethylsalicylate gel. Results of 2 clinical studies of effectiveness and bioavailability].

Fortschr. Med. 113(8) , 111-3, (1995)

Two clinical studies were carried out to investigate the efficacy and safety as well as the local and systemic availability of a hydroxyethylsalicyclate gel. A double blind, multicenter trial, involving 113 patients with nonarticular rheumatic back pain, reve...

Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation.

J. Pharm. Biomed. Anal. 60 , 51-8, (2012)

Capsaicinoids, salicylic acid, methyl and ethyl salicylate, glycol monosalicylate, camphor and l-menthol are widely used in topical formulations to relieve local pain. For each separate compound or simple mixtures, quantitative analysis methods are reported. ...

Topical penetration of commercial salicylate esters and salts using human isolated skin and clinical microdialysis studies.

Br. J. Clin. Pharmacol. 46(1) , 29-35, (1998)

The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controversy as to whether these agents are capable of direct penetrat...

Contact dermatitis from hydroxyethyl salicylate.

Contact Dermatitis 33(4) , 275-6, (1995)

Synergetic analgesic effect of the combination of arnica and hydroxyethyl salicylate in ethanolic solution following cutaneous application by transcutaneous electrostimulation.

Arzneimittelforschung 53(12) , 850-6, (2003)

A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy a...

Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate.

Dermatitis 22(3) , 171-2, (2011)

Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate.

Contact Dermatitis 47(2) , 120-1, (2002)