Senkirkine
Senkirkine structure
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Common Name | Senkirkine | ||
|---|---|---|---|---|
| CAS Number | 2318-18-5 | Molecular Weight | 365.42100 | |
| Density | 1.22g/cm3 | Boiling Point | 604.9ºC at 760 mmHg | |
| Molecular Formula | C19H27NO6 | Melting Point | 198ºC | |
| MSDS | Chinese USA | Flash Point | 319.6ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae): implications for toxicity.
Phytochemistry 108 , 137-46, (2014) Changes in plant chemical defenses after invasion could have consequences on the invaded ecosystems by modifying the interactions between plants and herbivores and facilitating invasion success. However, no comprehensive biogeographical studies have yet deter... |
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Determination of senkirkine and senecionine in Tussilago farfara using microwave-assisted extraction and pressurized hot water extraction with liquid chromatography tandem mass spectrometry.
Talanta 79(2) , 539-46, (2009) Tussilago farfara (Kuan Donghua) is an important Chinese herbal medicine which has been shown to contain many bioactive compounds and widely used to relieve cough and resolve phlegm. However, besides therapeutic bioactive compounds, this herb has been found t... |
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Interplant alkaloid variation and Senecio vernalis toxicity in cattle.
Vet. Hum. Toxicol. 43(3) , 147-51, (2001) Senecio vernalis and other plants containing pyrrolizidine alkaloids (PA) are implicated in the poisoning of cattle. The liver is a known target organ. In this study the content of the alkaloids senecionine (SCO), senkirkin (SKK) and seneciphyllin (SCP) and t... |
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Mutagenic activity of the pyrrolizidine alkaloids seneciphylline and senkirkine in Drosophila and their transfer into rat milk.
Food Chem. Toxicol. 22(3) , 223-5, (1984) Seneciphylline and senkirkine, two pyrrolizidine alkaloids that occur in animal feeds and medicinal herbs, respectively, have been tested for their ability to produce sex-linked recessive lethals in males of Drosophila melanogaster using the Basc test (3-day ... |
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Pyrrolizidine alkaloids from Senecio leucanthemifolius and Senecio rodriguezii.
Nat. Toxins 1(4) , 241-5, (1993) Two toxic pyrrolizidine alkaloids were isolated from Senecio leucanthemifolius and six from Senecio rodriguezii. Their structures were determined by spectroscopic methods. |
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Senkirkine.
IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 31 , 231-8, (1983)
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[Studies on the alkaloids of Senecio scandens growing in Guangdong].
Zhong Yao Cai 34(5) , 724-6, (2011) To study alkaloids of Senecio scandens growing in Guangdong.The rapid resolution liquid chromatography-electrospray ionization mass spectrometry (RRLC-ESI-MS/MS) was used to analyse alkaloids of Senecio scandens growing in Guangdong, and senkirkine was isolat... |
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Hepatotoxic pyrrolizidine alkaloids in the Mexican medicinal plant Packera candidissima (Asteraceae: Senecioneae).
J. Ethnopharmacol. 43(1) , 19-30, (1994) A study of the hepatotoxic pyrrolizidine alkaloids (PAs) contained in Packera candidissima (Greene) Weber & Löve (Senecio candidissimus Greene), a Mexican medicinal plant used for the treatment of kidney ailments and noted for its antiseptic properties, is re... |
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Anonamine, C19H27NO7, neosenkirkine, C19H27NO6, and hydroxysenkirkine, C19H27NO7.CH3OH. Macrocyclic secopyrrolizidine alkaloids from Senecio anonymus Wood.
Acta Crystallogr. C 44 ( Pt 9) , 1593-8, (1988) lambda(Mo K alpha) = 0.71069 A, T = 298 K. Anonamine (I) (12,21-dihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione): C19H27NO7, Mr = 381.2, monoclinic, C2, a = 24.247 (7), b = 8.766 (2), c = 9.072 (1) A, beta = 99.21 (2) degrees, U = 1903.3 (8) A3, Z = 4, D... |