4-Bromobenzenesulfonamide

4-Bromobenzenesulfonamide Structure
4-Bromobenzenesulfonamide structure
Common Name 4-Bromobenzenesulfonamide
CAS Number 701-34-8 Molecular Weight 236.086
Density 1.8±0.1 g/cm3 Boiling Point 360.7±44.0 °C at 760 mmHg
Molecular Formula C6H6BrNO2S Melting Point 163-167 °C
MSDS Chinese USA Flash Point 171.9±28.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and biological evaluation of linear phenylethynylbenzenesulfonamide regioisomers as cyclooxygenase-1/-2 (COX-1/-2) inhibitors.

Bioorg. Med. Chem. 14(15) , 5259-65, (2006)

A group of regioisomeric phenylethynylbenzenesulfonamides possessing a COX-2 SO2NH2 pharmacophore at the para-, meta- or ortho-position of the C-1 phenyl ring, in conjunction with a C-2 substituted-phenyl (H, OMe, OH, Me, F) group, were synthesized and evalua...

Metabolites of ebrotidine, a new H2-receptor antagonist, in human urine.

J. Pharm. Sci. 83(2) , 252-4, (1994)

Ebrotidine is a new H2-receptor antagonist which exhibits a remarkable ability for gastric mucosal protection. A preliminary metabolic pathway for this compound was proposed and the hypothetic metabolites were synthesized. The presence of ebrotidine and its m...

Determination of ebrotidine metabolites in overlapping peaks from capillary zone electrophoresis using chemometric methods.

Electrophoresis 22(1) , 71-6, (2001)

This paper illustrates the possibilities of chemometric methods in the resolution and quantification of various compounds in overlapping peaks from capillary electrophoresis. Ebrotidine and most of its metabolites were efficiently separated by capillary zone ...

Combining NMR and molecular modelling in a drug delivery context: investigation of the multi-mode inclusion of a new NPY-5 antagonist bromobenzenesulfonamide into beta-cyclodextrin.

Bioorg. Med. Chem. 12(2) , 447-58, (2004)

NMR spectroscopic and molecular modelling methods have been employed to describe the complexation of trans-N-4-[N'-(4-chlorobenzoyl)hydrazinocarbonyl]cyclohexylmethyl-4-bromobenzenesulfonamide, a new chemotype of NPY-5 antagonist, and beta-cyclodextrin, revea...

Preparation of novel cobalt (III) complexes with dithiocarbimates derived from sulfonamides. Oliveira MRL and Bellis VMD.

Transit. Met. Chem. 24(2) , 127-130, (1999)