lsd

lsd Structure
lsd structure
Common Name lsd
CAS Number 50-37-3 Molecular Weight 323.43200
Density 1.21g/cm3 Boiling Point 541.3ºC at 760mmHg
Molecular Formula C20H25N3O Melting Point 80 - 85ºC
MSDS Chinese USA Flash Point 281.2ºC
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.

J. Pharmacol. Exp. Ther. 350(3) , 589-604, (2014)

Brexpiprazole (OPC-34712, 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one) is a novel drug candidate in clinical development for psychiatric disorders with high affinity for serotonin, dopamine, and noradrenaline receptors. In particula...

Development and validation of a rapid turboflow LC-MS/MS method for the quantification of LSD and 2-oxo-3-hydroxy LSD in serum and urine samples of emergency toxicological cases.

Anal. Bioanal. Chem 407(6) , 1577-84, (2015)

Lysergic acid diethylamide (LSD) is a widely used recreational drug. The aim of the present study is to develop a quantitative turboflow LC-MS/MS method that can be used for rapid quantification of LSD and its main metabolite 2-oxo-3-hydroxy LSD (O-H-LSD) in ...

Effect of high-dose 1.25 dihydroxyvitamin D3 on remyelination in the cuprizone model.

APMIS 122(12) , 1178-86, (2014)

Vitamin D supplementation is increasingly recommended to patients with multiple sclerosis (MS). To study the effect of high-dose vitamin D on remyelination, female C57Bl/6 mice were demyelinated with dietary 0.2% cuprizone for 7 weeks. The mice received intra...

Determination of buprenorphine, fentanyl and LSD in whole blood by UPLC-MS-MS.

J. Anal. Toxicol. 37(3) , 159-65, (2013)

A sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method has been developed and validated for the quantification of buprenorphine, fentanyl and lysergic acid diethylamide (LSD) in whole blood. Sample preparation was per...

Covalent cross-linking of cell-wall polysaccharides through esterified diferulates as a maize resistance mechanism against corn borers.

J. Agric. Food Chem. 63(8) , 2206-14, (2015)

There is strong evidence to suggest that cross-linking of cell-wall polymers through ester-linked diferulates has a key role in plant resistance to pests; however, direct experimentation to provide conclusive proof is lacking. This study presents an evaluatio...

Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract.

Int. J. Cosmet. Sci. 37(2) , 253-8, (2015)

Vitis vinifera 'muscat hamburg' (Vitaceae) is a blue-black grape variety commonly found in Pakistan. It has been consumed and used in traditional medicine for centuries. Compared to other grapes, M. hamburg records one of the greatest amount of polyphenols an...

Comparison of industrially viable pretreatments to enhance soybean straw biodegradability.

Bioresour. Technol. 194 , 1-6, (2015)

This study explores acid and alkaline pretreatments in order to enhance soybean straw biodegradability. The effects of sulfuric acid and sodium hydroxide for different pretreatment times at 30°C and 121°C on biomass dissolution and the subsequent enzymatic hy...

A modified bilateral carotid artery stenosis procedure to develop a chronic cerebral hypoperfusion rat model with an increased survival rate.

J. Neurosci. Methods 255 , 115-21, (2015)

Bilateral carotid artery occlusion (2-vessel occlusion, 2VO) in rats is a classic and frequently used approach to develop an animal model of chronic cerebral hypoperfusion. However, this method results in substantial mortality in rats.We investigated whether ...

Localized experimental bone metastasis drives osteolysis and sensory hypersensitivity at distant non-tumor-bearing sites.

Breast Cancer Res. Treat. 153 , 9-20, (2015)

Patients with breast cancer metastasis to bone suffer from inadequate pain relief. Animal models provide increased understanding of cancer-induced bone and sensory alterations. The objective of this study was to investigate the measures of pain at distant non...

Impact of an autologous oxygenating matrix culture system on rat islet transplantation outcome.

Biomaterials 52 , 180-8, (2015)

Disruption of the pancreatic islet environment combined with the decrease in oxygen supply that occurs during isolation leads to poor islet survival. The aim of this study was to validate the benefit of using a plasma-based scaffold supplemented with perfluor...