m-hydroxybenzoylecgonine
m-hydroxybenzoylecgonine structure
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Common Name | m-hydroxybenzoylecgonine | ||
|---|---|---|---|---|
| CAS Number | 129944-99-6 | Molecular Weight | 305.32600 | |
| Density | 1.38g/cm3 | Boiling Point | 513.9ºC at 760mmHg | |
| Molecular Formula | C16H19NO5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 264.6ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Application of a validated high-performance liquid chromatography-mass spectrometry assay to the analysis of m- and p-hydroxybenzoylecgonine in meconium.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 820(1) , 151-6, (2005) A high-performance liquid chromatography (HPLC)-mass spectrometry (MS) assay, already validated for opiates and cocaine in meconium, has been re-applied for determination of m- and p-hydroxybenzoylecgonine, using nalorphine as the internal standard. Methodolo... |
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m-Hydroxybenzoylecgonine: an important contributor to the immunoreactivity in assays for benzoylecgonine in meconium.
J. Anal. Toxicol. 17(6) , 348-52, (1993) Meconium has been reported to be a more suitable specimen than maternal or neonatal urine for detecting fetal exposure to cocaine. In a study comparing various immunoassays with gas chromatography/mass spectrometry (GC/MS), several unexplained discrepancies a... |
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Complete automation of solid-phase extraction with subsequent liquid chromatography-tandem mass spectrometry for the quantification of benzoylecgonine, m-hydroxybenzoylecgonine, p-hydroxybenzoylecgonine, and norbenzoylecgonine in urine--application to a high-throughput urine analysis laboratory.
J. Anal. Toxicol. 32(8) , 577-85, (2008) A fully automated system utilizing a liquid handler and an online solid-phase extraction (SPE) device coupled with liquid chromatography-tandem mass spectrometry (LC-MS-MS) was designed to process, detect, and quantify benzoylecgonine (BZE), meta-hydroxybenzo... |
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Simultaneous GC-MS analysis of meta- and para-hydroxybenzoylecgonine and norbenzoylecgonine: a secondary method to corroborate cocaine ingestion using nonhydrolytic metabolites.
J. Anal. Toxicol. 24(7) , 482-8, (2000) Positive benzoylecgonine (BZE) urinalysis results are sometimes challenged in legal and administrative proceedings on the grounds that the presence of BZE is due to the addition of cocaine to the urine sample with subsequent in vitro hydrolysis to BZE. Conseq... |
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Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine.
J. Anal. Toxicol. 34(2) , 57-63, (2010) Urinary excretion of ecgonine (EC) was compared to that of cocaine, benzoylecgonine, ecgonine methyl ester and minor metabolites, meta-hydroxybenzoylecgonine, para-hydroxybenzoylecgonine, and norbenzoylecgonine, following controlled administration of oral, in... |
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Sensitive method for detection of cocaine and associated analytes by liquid chromatography-tandem mass spectrometry in urine.
J. Anal. Toxicol. 33(8) , 447-55, (2009) Cocaine (COC) is a potent CNS stimulant that is metabolized to benzoylecgonine (BE) and further metabolized to minor metabolites such as m-hydroxybenzoylecgonine (m-HOBE). COC is also metabolized to norcocaine (NC). Cocaethylene (CE) is formed when cocaine an... |
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m-hydroxy benzoylecgonine recovery in fetal guinea pigs.
Drug Metab. Dispos. 28(3) , 335-8, (2000) Recently, meta-hydroxybenzoylecgonine (m-OH BE) was identified by gas chromatography-mass spectroscopy during quantitative analysis for cocaine. Identification of m-OH BE in addition to the routinely identified benzoylecgonine by gas chromatography-mass spect... |
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GC/MS analysis of m-hydroxybenzoylecgonine in urine. Forensic implication in cocaine use.
Clin. Lab. Med. 18(4) , 699-704, ix, (1998) m-Hydroxybenzoylecgonine (m-OH-BE) and d3-m- hydroxybenzoylecgonine (d3-m-OH-BE) have been synthesized, and a GC/MS procedure with d3-m-OH-BE as internal standard has been developed. Among 24 human urine specimens that were positive for BE, all of them have s... |