Cyclizine Hydrochloride

Cyclizine Hydrochloride Structure
Cyclizine Hydrochloride structure
Common Name Cyclizine Hydrochloride
CAS Number 303-25-3 Molecular Weight 302.84200
Density N/A Boiling Point 363.7ºC at 760mmHg
Molecular Formula C18H23ClN2 Melting Point 258-260ºC
MSDS N/A Flash Point 159.1ºC
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Differential thermodynamic driving force of first- and second-generation antihistamines to determine their binding affinity for human H1 receptors.

Biochem. Pharmacol. 91(2) , 231-41, (2014)

Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and sec...