(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)
![(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1) Structure](https://image.chemsrc.com/caspic/225/5685-86-9.png)
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1) structure
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Common Name | (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1) | ||
|---|---|---|---|---|
| CAS Number | 5685-86-9 | Molecular Weight | 398.43100 | |
| Density | N/A | Boiling Point | 324.4ºC at 760 mmHg | |
| Molecular Formula | C17H22N2O7S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 150ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phenotypic characterization of two Ancylostoma caninum isolates with different susceptibilities to the anthelmintic pyrantel.
Antimicrob. Agents Chemother. 52 , 3980-3986, (2008) The anthelmintic pyrantel plays an important role in the control of gastrointestinal helminths of humans and domestic animals. Despite the demonstration of pyrantel resistance in several helminth species over the last 20 years, the resistance mechanism remain... |
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Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle.
J. Pharmacol. Exp. Ther. 302 , 853, (2002) Paraherquamide is a novel natural anthelmintic product with a mode of action that is incompletely characterized. Nicotine and cholinergic-anthelmintic agonists of different chemical classes were used to produce contraction in Ascaris muscle strips. Paraherqua... |
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The mechanism of the paralysing action of tetramisole on Ascaris somatic muscle.
Br. J. Pharmacol. 38 , 602-607, (1970) 1. Tetramisole (100 mug/ml) paralysed live Ascaris in 3 min.2. Tetramisole (10 mug/ml) caused a sustained contraction of the isolated somatic muscles of the worm. This contraction was not blocked by curare nor by piperazine.3. Tetramisole reduced the resting ... |
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The kinetic disposition of pyrantel citrate and pamoate and their efficacy against pyrantel-resistant Oesophagostomum dentatum in pigs.
Int. J. Parasitol. 26(12) , 1375-80, (1996) The pharmacokinetic disposition of pyrantel after intravenous (i.v.) and oral (p.o.) administration as the citrate and p.o. administration as the pamoate salt was determined in pigs. Following i.v. administration pyrantel was quickly cleared from the bloodstr... |
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In vitro characterization of anthelmintic susceptibility of field isolates of the pig nodular worm Oesophagostomum spp., susceptible or resistant to various anthelmintics.
Int. J. Parasitol. 26(7) , 733-40, (1996) A larval development assay (LDA) and an egg hatch paralysis assay (EHPA) were used to measure the sensitivity to anthelmintics of eggs and larvae of nodular worms (Oesophagostomum spp.) in pigs. The tests were carried out using in vivo defined resistant and s... |
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Relative efficacies of pyrantel tartrate and pyrantel citrate against Oesophagostomum sp in swine.
Am. J. Vet. Res. 42(5) , 871-2, (1981) The relative efficacies of pyrantel tartrate and of pyrantel citrate against Oesophagostomum sp in swine were evaluated in a controlled-critical study and the efficacy of pyrantel citrate in a field trial. In the controlled-critical study, pigs naturally infe... |