Chicoric acid
Chicoric acid structure
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Common Name | Chicoric acid | ||
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| CAS Number | 70831-56-0 | Molecular Weight | 474.371 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 785.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C22H18O12 | Melting Point | 206 °C | |
| MSDS | USA | Flash Point | 272.9±26.4 °C | |
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[Simultaneous determination of five organic acids in Kudiezi injection by HPLC].
Zhongguo Zhong Yao Za Zhi 38(19) , 3287-90, (2013) The aim was to develop a high performance liquid chromatography method for simultaneous determination of five organic acids in Kudiezi injection. The Diamonsil C18 column (4.6 mm x 200 mm, 5 microm) was adopted with acetonitrile and water as the mobile phase ... |
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Application of an online post-column derivatization HPLC-DPPH assay to detect compounds responsible for antioxidant activity in Sonchus oleraceus L. leaf extracts.
J. Pharm. Pharmacol. 65(2) , 271-9, (2013) To use an online assay to identify key antioxidants in Sonchus oleraceus leaf extracts and to investigate the effect of leaf position and extraction conditions on antioxidant concentration and activity.Separation of phytochemicals and simultaneous assessment ... |
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Echinacea alkylamides modulate induced immune responses in T-cells.
Fitoterapia 79(1) , 53-8, (2008) The effects of Echinacea and several of its phytochemical components on NFkappaB expression by Jurkat cells (a human T-cell line) were investigated in vitro. In the absence of stimulation, Echinacea and its components exerted no significant effect on basal NF... |
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Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid.
Biotechnol. Lett. 29(8) , 1179-82, (2007) Adventitious roots of Echinacea purpurea were cultured in airlift bioreactors (20 l, 500 l balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige and Skoog (MS) medium with 2 mg indole butyric acid l(-1) and 50 g sucrose l(-... |
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Augmentation of immune response by chicoric acid through the modulation of CD28/CTLA-4 and Th1 pathway in chronically stressed mice.
Neuropharmacology 60(6) , 852-60, (2011) This study demonstrates the protective effect of chicoric acid (CA) on chronic restraint stress-induced altered T lymphocyte subset distribution and corresponding cytokine secretion patterns in experimental Swiss albino mice. CA has the potential to restore d... |
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A cross-over inhibitor of the botulinum neurotoxin light chain B: a natural product implicating an exosite mechanism of action.
Chem. Commun. (Camb.) 47(6) , 1713-5, (2011) Clostridium botulinum produces the most lethal toxins known to man, as such they are high risk terrorist threats, and alarmingly there is no approved therapeutic. We report the first cross-over small molecule inhibitor of these neurotoxins and propose a mecha... |
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Chicoric acid regulates behavioral and biochemical alterations induced by chronic stress in experimental Swiss albino mice.
Pharmacol. Biochem. Behav. 99(3) , 342-8, (2011) The present study was taken up to see the effect of chicoric acid (CA) on behavioral and biochemical alterations induced by chronic restraint stress in experimental Swiss albino mice. CA at 1mg/kg dose level exhibited considerable antidepressant activity as s... |
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Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis.
J. Ethnopharmacol. 143(3) , 914-9, (2012) Echinacea is a top-selling herbal supplement that acts as immunostimulant. It has been used to treat common cold, coughs, bronchitis and upper respiratory infections. It is also a popular product used in anticancer therapy. The cytotoxic effects of Echinacea ... |
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Biomimetic formation of chicoric-acid-directed luminescent silver nanodendrites.
Nanotechnology 23(29) , 294011, (2012) In this work, we report the formation of well-defined silver nanodendrites via biomineralization under mild conditions in a single step, in the presence of the plant phytohormone chicoric acid (CA), a well-known HIV-I integrase inhibitor. CA played a dual rol... |
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Inhibition of stromelysin-1 by caffeic acid derivatives from a propolis sample from Algeria.
Planta Med. 77(10) , 999-1004, (2011) Stromelysin-1 (matrix metalloproteinase-3: MMP-3) occupies a central position in collagenolytic and elastolytic cascades, leading to cutaneous intrinsic and extrinsic aging. We screened extracts of a propolis sample from Algeria with the aim to isolate compou... |