Benzotrichloride
Benzotrichloride structure
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Common Name | Benzotrichloride | ||
|---|---|---|---|---|
| CAS Number | 98-07-7 | Molecular Weight | 195.47400 | |
| Density | 1.38 g/mL at 25 °C(lit.) | Boiling Point | 219-223 °C760 mm Hg(lit.) | |
| Molecular Formula | C7H5Cl3 | Melting Point | −7.5-−7 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 207 °F | |
| Symbol |
GHS05, GHS06, GHS08 |
Signal Word | Danger | |
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Solid-phase microextraction fiber development for sampling and analysis of volatile organohalogen compounds in air.
J. Environ. Health. Sci. Eng. 12(1) , 123, (2014) A green, environmental friendly and sensitive method for determination of volatile organohalogen compounds was described in this paper. The method is based on a homemade sol-gel single-walled carbon nanotube/silica composite coated solid-phase microextraction... |
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Determination of trace level genotoxic impurities in small molecule drug substances using conventional headspace gas chromatography with contemporary ionic liquid diluents and electron capture detection.
J. Chromatogr. A. 1361 , 217-28, (2014) Ionic liquids (ILs) were used as a new class of diluents for the analysis of two classes of genotoxic impurities (GTIs), namely, alkyl/aryl halides and nitro-aromatics, in small molecule drug substances by headspace gas chromatography (HS-GC) coupled with ele... |
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Toxicity of trichlorotoluene isomers: a 28-day feeding study in the rat.
J. Environ. Sci. Health B 19(2) , 183-91, (1984) Groups of 10 male and 10 female rats were fed alpha,alpha,alpha-, alpha,2,6- or 2,3,6- trichlorotoluene (TCT) in their diet at 0, 0.5, 5.0, 50 or 500 ppm for 28 days. Growth rate and food consumption were not affected by treatment. No deaths occurred. Signifi... |
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K-ras mutations in benzotrichloride-induced lung tumors of A/J mice.
Carcinogenesis 14(6) , 1247-9, (1993) Benzotrichloride (BTC) is used extensively as a chemical intermediate in the synthesis of benzoyl chloride and benzoyl peroxide. Epidemiological data suggest that BTC is a human lung carcinogen. BTC is also a carcinogen in the A/J mouse lung tumor bioassay. A... |
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A mortality study of workers in a factory manufacturing chlorinated toluenes.
Ann. Occup. Hyg. 27(2) , 173-82, (1983)
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Lung tumor induction in strain A mice with benzotrichloride.
Cancer Lett. 33(2) , 167-73, (1986) Benzotrichloride (BTC) is used in the synthesis of benzoyl chloride and benzoyl peroxide. Epidemiological data suggest that BTC is a human lung carcinogen. In the present study, BTC was evaluated for its ability to induce lung adenomas in strain A/J mice. Fou... |
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A cohort mortality study of employees exposed to chlorinated chemicals.
Am. J. Ind. Med. 14(4) , 417-31, (1988) The cohort of this historical prospective mortality study consisted of 697 male employees at a chlorination plant. A majority of the cohort was potentially exposed to benzotrichloride, benzyl chloride, benzoyl chloride, and other related chemicals. The mortal... |
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Carcinogenicity of benzotrichloride administered to mice by gastric intubation.
Ind. Health 31(3) , 127-31, (1993) Epidemiological studies suggest that benzotrichloride (BTC) is a human carcinogen. In the present study, BTC was tested to evaluate its ability to induce lung tumors as a result of systemic exposure. Administration of BTC by gastric intubation, 2.0-0.0315 mic... |
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Vibrational spectroscopic studies, NLO, HOMO-LUMO and electronic structure calculations of α,α,α-trichlorotoluene using HF and DFT.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 94 , 53-64, (2012) FT-IR and FT-Raman spectra of α,α,α-trichlorotoluene have been recorded and analyzed. The geometry, fundamental vibrational frequencies are interpreted with the aid of structure optimizations and normal coordinate force field calculations based on density fun... |
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Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines.
Environ. Mol. Mutagen. 52(7) , 547-61, (2011) Included among the quantitative high throughput screens (qHTS) conducted in support of the US Tox21 program are those being evaluated for the detection of genotoxic compounds. One such screen is based on the induction of increased cytotoxicity in seven isogen... |