DABCO
DABCO structure
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Common Name | DABCO | ||
|---|---|---|---|---|
| CAS Number | 280-57-9 | Molecular Weight | 112.17 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 174.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H12N2 | Melting Point | 156-159 °C(lit.) | |
| MSDS | Chinese | Flash Point | 62.2±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.
Stroke 46(3) , 835-42, (2015) Ischemic stroke has been shown to cause hypermetabolism of glucose in the ischemic penumbra. Experimental and clinical data indicate that infarct-related systemic hyperglycemia is a potential therapeutic target in acute stroke. However, clinical studies aimin... |
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MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b.
J. Immunol. 194(5) , 2079-88, (2015) Dendritic cells (DCs) are specialized APCs with the ability to prime naive T cells. DCs first sample Ags from the environment and then orchestrate their processing and loading onto MHC class II (MHC II) Ag-presenting molecules in lysosomes. Once MHC II molecu... |
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The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection.
J. Virol. 89(1) , 443-53, (2014) During DNA encapsidation, herpes simplex virus 1 (HSV-1) procapsids are converted to DNA-containing capsids by a process involving activation of the viral protease, expulsion of the scaffold proteins, and the uptake of viral DNA. Encapsidation requires six mi... |
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Comparison of [corrected] actin- and glass-supported phospholipid bilayer diffusion coefficients.
Biophys. J. 108(8) , 1946-53, (2015) The formation of biomimetic lipid membranes has the potential to provide insights into cellular lipid membrane dynamics. The construction of such membranes necessitates not only the utilization of appropriate lipids, but also physiologically relevant substrat... |
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HIV-1 and its gp120 inhibits the influenza A(H1N1)pdm09 life cycle in an IFITM3-dependent fashion.
PLoS ONE 9(6) , e101056, (2014) HIV-1-infected patients co-infected with A(H1N1)pdm09 surprisingly presented benign clinical outcome. The knowledge that HIV-1 changes the host homeostatic equilibrium, which may favor the patient resistance to some co-pathogens, prompted us to investigate wh... |
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Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study.
Life Sci. 116(1) , 8-15, (2014) The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice.Carvacrol treatment (12.5-50mg/kgs.c.) once daily for 15days was started 24h after injection of the sarcoma cells in the hind paw (s.... |
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Ciliary abnormalities in senescent human fibroblasts impair proliferative capacity.
Cell Cycle 13(17) , 2773-9, (2014) Somatic cells senesce in culture after a finite number of divisions indefinitely arresting their proliferation. DNA damage and senescence increase the cellular number of centrosomes, the 2 microtubule organizing centers that ensure bipolar mitotic spindles. C... |
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Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature.
PLoS ONE 10(4) , e0123553, (2015) Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and neovascularization. Pe... |
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GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination.
J. Neurosci. Res. 93(2) , 285-95, (2014) The γ-aminobutyric acid (GABA) type B receptor has been implicated in glial cell development in the peripheral nervous system (PNS), although the exact function of GABA signaling is not known. To investigate GABA and its B receptor in PNS development and dege... |
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Pharmacological inhibition of dynamin II reduces constitutive protein secretion from primary human macrophages.
PLoS ONE 9(10) , e111186, (2014) Dynamins are fission proteins that mediate endocytic and exocytic membrane events and are pharmacological therapeutic targets. These studies investigate whether dynamin II regulates constitutive protein secretion and show for the first time that pharmacologic... |